Reproductive embryology Flashcards

1
Q

Where does the development of the urogenital tract originate?

A

Intermediate mesoderm

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2
Q

What are the 3 sets of kidneys that develop?

A

The pronephros
The mesonephros
The metanephros

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3
Q

What is the cloaca?

A

The common opening for the gut tube and the urinary system - humans don’t have this after birth but birds do

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4
Q

When does the mesonephros form?

A

Around 6 weeks

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5
Q

What forms the gonadal ridge?

A

Thickening of the medial part of the mesonephric ridge

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6
Q

What is an indifferent gonad?

A

The gonad before it has differentiated into being male or female - impossible to tell gender

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7
Q

What is the paramesonephric duct?

A

A tube that forms by invaginating laterally to the mesonephric duct

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8
Q

What are the openings of the paremesonephric ducts?

A

Cranially - Peritoneal cavity

Caudally - Cross ventral to mesonephric ducts into the urogenital sinus

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9
Q

What are other names for the mesonephric duct and the paramesonephric duct?

A

Mesonephric - Wolffian

Paramesonephric - Mullerian

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10
Q

What happens to the mesonephric duct in males?

A

Develops into epididymis. vas deferens, and seminal vesicle

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11
Q

What happens to the paramesonephric duct in males?

A

Degenerates

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12
Q

What happens to the urogenital sinus in males?

A

Forms the bladder, urethra, and prostate

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13
Q

What happens to the mesonephric duct in females?

A

Degenerates

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14
Q

What happens to the paramesonephric duct in females?

A

Develops into the fallopian tube, uterus, cervix, and upper part of the vagina

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15
Q

What happens to the urogenital sinus in females?

A

Forms the bladder and lower part of the vagina

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16
Q

What determines what the indifferent gonad will become?

A

An area on the Y chromosome called Sex Determining Region Y (SRY)

17
Q

What causes SRY to cause indifferent gonads to develop into testis?

A

It encodes for a protein called Testis Determining Factor (TDF)

18
Q

When are Leydig cells in the testis produced?

A

Week 8