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BMSC208 > Repro 3 > Flashcards

Repro 3 Flashcards

1
Q

GnRH

A

Is secreted in a pulsatile manner

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2
Q

How is GnRH activated

A
  1. Pulsatile activity in kisspeptin neurons stimulate GnRH neurons to release GnRH
  2. GnRH binds to GnRH receptor on gonadotropes in the anterior pituitary to release LH and FSH
  3. LH and FSH act on gonads to stimulate hormone secretion and facilitate gamete production
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3
Q

Environmental factors influence reproduction

A

In looked in females
Nutritional factors
Level of physical activity
Circadian Rhythm

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4
Q

Environmental estrogens

A

can bind and activate estrogen receptors

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5
Q

Testes

A

Produces hormones and gametes

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6
Q

External genetalia in males

A

Penis
Urethra
Corpus Spongiosum (keeping the urethra open)
Corpova cavernosa (Creating erection)
Glans, prepuse (head of penis)

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7
Q

Scrotum

A

External sac testes migrate into
Sperm development requires lower body temperature

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8
Q

Internal genetilia

A

Accessory glands

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9
Q

What are the accessory glands

A

Seminal Vesicle
Prostate gland
Bublourethral gland

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10
Q

Function of internal genetilia

A

Empty secretions into the urethra

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11
Q

Prostate

A

Continually grows through a males life

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12
Q

What is responsible to the formation of external genetilia and prostate

A

DHT

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13
Q

Finasteride

A

DHT inhibition (Slows down Prostate hypertrophy)

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14
Q

What do testis produce

A

Sperm and Hormones

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15
Q

Bulk of tests mass is

A

Seminiferous tubule

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16
Q

What is the site of sperm production

A

Seminiferous Tubule

17
Q

Leydig cell produces

A

Testosterone

18
Q

Sertoli cells

A

Contains tight junctions with adjacent Sertoli cells forming a blood testes barrier between tubule lumen and interstitial space

19
Q

Male pseudohemaphrodites

A

Lack the enzyme to convert testosterone to DHT

20
Q

Sperm production

A

Germ cells (spermatogonium) reside just inside the basal lamina of seminiferous tubules
As spermatocytes differentiate to sperm they move towards the tubule lumen
Sertoli tight junctions break and reform around the migrating cells

21
Q

Structure of sperm

A

Chromatin condenses
Microtubule extension
Acrosome forms a cap over the nucleus
Mid piece: Mitochondria for energy
Spermatogonium to free sperm

22
Q

What is mid space composed of

A

Mitochondria

23
Q

Where do sperm mature

A

epididymis

24
Q

FSH binds to

A

Sertoli cells

25
Q

LH tagets

A

interstitial leydig cells promoting testosterone production

26
Q

Primary components of semen

A

Nutrients
Buffers
Chemicals to increase sperm motility
Prostaglandins
Immunoglobulins

27
Q

The cells that primarily regulate spermatogenesis are

A

Sertoli cells

28
Q
A

BMSC208 (20 decks)

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