GI 5 Flashcards

1
Q

Three main categories of pancreatic secretion

A
  1. Endocrine secretion
  2. Digestive enzyme secretion
  3. Bicarbonate secretion
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2
Q

Pancreas are composed of

A

Contains endocrine secretory epithelium

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3
Q

Exocrine secretory epithelium

A

Digestive enzymes and NaHCO3

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4
Q

How are pancreatic enzymes released

A

by zymogens

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5
Q

how are pancreatic zymogens activated

A

Tripsinogen converted to trypsin by enteropeptidase (Brush border enzyme)
Trypsin activates zymogens

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6
Q

Role of bicarbonate in pancreas

A

They are produced in duct cells and neutralizes acid entering from stomach

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7
Q

Cystic fibrosis alters

A

Pancreas secretion

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8
Q

gallbladder

A

Storage redevoir for liver

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9
Q

Liver secretes

A

Bile

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10
Q

What id bile secreted by

A

Hepatocytes

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11
Q

What is bile

A

non enzymatic solution
3 main components:
bile salts
bile pigments
cholestrol

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12
Q

Main role of bile is

A

Lipid Digestion

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13
Q

Bile

A

Dissociates the lipid molecule (takes it apart)

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14
Q

What inhibits gastric acid secretion

A

Somatostatin

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15
Q

Steps of Fat absorption

A
  1. Bile salts from live coat fat droplets
  2. Pancreatic lipase and collapse break down fats into monoglycerides and fatty acids stored in micelles
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16
Q

Cholesterol are packed in

A

Chylomicrons

17
Q

How are chylomicrons released

A

By the lymphatic system

18
Q

Bile

A

It recycles

19
Q

Gallstones

A

hardened deposits likely due to excess cholesterol or bilirubin
Upper right abdominal pain, jaundice

20
Q

Steps of carbohydrates digestion

A

Amylase (salivary and pancreatic) break down glucose polymers to disaccharides (maltose)
Disaccharides are broken down into monosaccharides

21
Q

two categories of protein digestion

A

Endopeptidases
Exopeptidases

22
Q

Endopeptidases

A

Cleave proteins to smaller peptides
Attack Peptide bonds in the amino acid chain forming fragments
- Released as zymogens
- Pepsin, trypsin and chymotrypsin

23
Q

Exopeptidase

A

Release single amino acids for peptides one at a time

24
Q

Aminopeptidase

A

Amino terminal end enzyme

25
Carboxypeptidase
Carboxy terminal end (most of it)
26
Digestive enzymes in the stomach are produced in
Chief cells
27
ECL cells secrete
histamine
28
Protein absorption
Mostly free amino acids
29
olingopeptide transporter
H+ cotransporter
30
Larger peptides are transported
By transcytosis (Relatively small)
31
Vitamin and Mineral absorption
Fat soluble vitamins (A, D, E and K absorbed with fats Water soluble C and B are absorbed by mediated transport B12 is absorbed in the ileum after forming a complex with intrinsic factor released from parietal cells Mineral absorption is usually by active transport
32