GI 6 Flashcards
Activation of most pancreatic zymogen depends on
Trypsin
Sources of regulation in the intestinal phase
Acidity
Fat
Amino acids
Hypertonicity
Distension
When substances move into intestine what happens in the stomach
Reduced motility and secretions in the stomach
What is intestinal motility influenced by
ENS neurons (Myenteric plexus)
Segmental contraction
mixing food
Peristaltic Contractions
Responsible for forward motion
Mo cells
Secrete motion
Possibly stimulated by alkaline pH
Accessory secretion are _________
Long reflexes
Types of GI peptides
S cells, I cells, K cells, L cells
S cells
Secretin
I cells
CKK
K cells
Glucose dependent insulinotropic peptide (GIP)
l CELLS
Glucagon like peptide 1 (GLP-1)
When do pancreatic secretions start
Cephalic phase and Gastric phase
what are associated with pancreatic secretions
Gastrin and parasympathetic neurons
enteropancreatic reflex
- Small intestine influencing the pancreas
S cells
Secretin secreted from S cells
Stimulated by acid coming in from duodenum
Role of S cells
Stimulates bicarbonate secretion from pancreas
(Lots of bicarbonate to regulate acid in the stomach)
Secondary mechanism of S cells
Stimulated bile secretion from liver
Inhibit of the Gastric acid secretion and gastric motility
Carbohydrates are primarily absorbed by
Monosaccharides
I cells
Cholecystokinin (CKK)
Stimulated by the presence of fatty acids and amino acids in chyme
Primary role of I cells
Regulates pancreatic enzyme secretion
Secondary role of I cells
Regulates bile secretion
K cells and L cells
Gastro inhibitory peptides
Glucagon like peptide
Glucose homeostais
Promotes production of insulin
Insulin is secreted in the pancreas
Inhibit gastric acid secretion and motility
