GI 2 and 3 Flashcards

1
Q

Digestion

A

Chemical and mechanical breakdown of food into absorbable units

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2
Q

Secretion

A

Movement of material from cells of the lumen or ECF

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3
Q

Absorbtion

A

Movement of material from GI lumen to ECF

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4
Q

mobility

A

Movement of material through the GI tract as a result of muscle contraction

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5
Q

Challenges of the digestive system

A

Avoiding autodigestion
Defense
Maintaining mass balance

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6
Q

Avoiding Autodigestion

A

Breaking food down into small enough molecules to be absorbed without digesting the cell of the GI tract

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7
Q

Defense

A

Absorbing water and nutrients while preventing bacteria, viruses and other pathogens from entering the body.

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8
Q

mechanisms of defense

A

Mucus, digestive enzymes, acid and the largest collection of lymphoid tissue

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9
Q

Fluid secretions

A

Water, Digestive Enzymes and Mucus

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10
Q

Water

A

Ions are transported from ECF into the Lumen
Creates osmotic gradient for water movement

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11
Q

Digestive Enzymes

A
  • Exocrine glands (Salivary and pancreas)
  • Epithelial cells in stomach and small intestine
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12
Q

Zymogen

A

Inactive enzymes

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13
Q

Mucus

A

Viscous glycoprotein (mucins) secretions that protect GI cells and lubricate the contents

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14
Q

Most fluid secretion fascilitates

A

Digestion

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15
Q

Two purposes of motility

A
  1. Moves food from mouth to anus
  2. Mechanically mixing food breaks it into uniformly small particles
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16
Q

Muscles involved in motility

A

Skeletal and Smooth Muscle

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17
Q

How are smooth muscles of motility modifies

A

Chemical and mechanical input from nerves
Hormones and paracrine signals

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18
Q

Phasic smooth muscle

A

Cycle of contraction and relaxation
In esophagus, stomach and large intestile

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19
Q

Slow wave

A

Modified by chemical input from neurons, hormones and paracrine signals

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20
Q

Where do slow waves likely orginate from

A

Interstitial cells of cajal (icc)

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21
Q

ICC

A

Modified smooth muscle cells serving as the pacemaker for slow wave activity

22
Q

Migrating Motor Complex

A

Starts in stomach and passes from section to section terminating at the ilum (Through the small intestine)
Inbetween meals.
Sweeps food remnants and bacteria out of the upper GI tract and into the large intestine

23
Q

Peristaltic Contractions

A

During or following a meal
Circular layer of smooth muscle: Contracts responsible for forward movement

24
Q

Segmental Contractions

A

Are responsible for mixing
Circular and longitudinal contractions

25
Primarily Regulated functions of GI system
Motility and secretion
26
Neural regulation
Submucosal and myenteric plexuses from the ENS Neurons synapse with each other. Smooth muscles, glands and epithelial cells Short reflexes integrated entirely within the ENS Long reflexes integrated within the CNS
27
GI peptides
Hormones, neuropeptides and cytokines
28
Similarities of ENS and CNS
intrinsic neurons: Entirely within the GI tract Neurotransmitters and neuromodulators Has glial support cells: Similar to astrocytes Diffusion barrier Integrating center
29
Short reflexes
Original in the ENS, and carried out entirely within the wall of the gut
30
Mycentric plexus control
Motility
31
Submucosal plexus control
Secretion from GI secretory cells
32
Long reflexes
Integrated in the CNS
33
When a long reflex begins in the brain
Cephalic reflex
34
PNS
Enhances GI functioning
35
Which region of the GI tract has a large amount of bacteria
Large Intestine
36
Movement from lumen of the GI tract into the ECF
Absorption
37
Two families of HOEMONES
Gastrin Family secretion Family
38
3 Phases within the digestive system
Cephalic/oral phase Gastric Phase intestinal phase
39
How is cephalic phase increased
From parasympathethietic output from medulla
39
Cephalic phase
Digestive processes can actually start before food enters the mouth and are reinforced once food enters the GI tract In a feedforward fashion
40
once food enters the mouth
Mastification (Increased Parasympathethetic output)
41
3 main salivary glands
Parotid Gland Sublingual Gland Submandibular Gland
42
4 functions of the salivary glands
Softens and moisten food Digestion of Carbohydrates (Amylase) Dissolve foods (Taste) Defence (Lysozome)
43
Where are secretory cells of saliva found
Acini
44
All glands are not
Identical
45
Parotid
Watery solution with amylase (Just serous cells)
46
Submandibular
Similar to parotid plus some mucus. Many serous, some mucus cells
47
Sublingual
Mainly mucus cells
48
Degutition
Reflex that pushes the bolus of good into the esophagus
49
What stares swallowing
Tongue pushing up
50
swallowing centre
medulla
51