GI 4 Flashcards
The Cephalic phase is initiated
In the brain (Long reflex)
Stimuli for acid secretion
Apical H+/K+ ATPase, CL- and K+ transporters stored in vesicles
Gastrin, Histamine, ACh, Somatostain causę exocytosis and insertion of apical transporters
What kind of a reflex is Gastric Acid secretion
Long Reflex
D cells
Inhibit parietal cells
Gastric digestive enzyme secretion
Stimulated by acid secretion via short reflex
Stimulates chief cells
ECL
Histamine activates H2 receptors on parietal cells to stimulate Hcl secretion
Parietal cell
Intrinsic factor
Forms a complex with Vit B12 so it can be absorbed
D cell
Somatostatin
Break for Acid secretion
What are mucus and HCO3- Secreted from
Mucous cells
Mucus layer is a ________
Physical barrier
Peptic Ulcer
A sore or break in the lining of the stomach or duodenum
Reason of peptic ulcer
Excessive Acid Production
- Gastrin
- Secreting tumors
Anti inflammatory Drugs
H Pylori
Bacteria caused peptic ulcers
Major reason of peptic ulcer
Gastic absorbtion?
Not a lot
In intestinal phase what combination go contractions occur
Segmental and peristaltic contractions