renal, testicular and penile cancer Flashcards
most common benign tumour
oncocytoma
what does an oncocytoma look like on radiograph
has got a central scar/spoke wheel pattern
symptoms of oncocytoma
mostly incidental
- loin pain
- haematuria
what disease is angiomyolipoma associated wtih
tuberous sclerosis
what are the three pathology components of angiomyolipoma
- blood vessels
- immature smooth muscle
- fat
what is Wunderlich’s syndrome
angiomeolipoma presenting with a massive retroperitoneal bleed
treatment for angiomyopiloma
where do renal cell carcinomas arise from
proximal convoluted tube
genetic cause of a clear cell carcinoma
loss of Von Hippel Landau gene on short of chromosome 3
who gets collecting duct carcinomas
young people
-very rare
who gets medullary cell carcinomas
young sickle cell patients
-poor prognosis
treatment for small RCC tumours
- surveillance
- ablation in fit elderly
- partial nephrectomy
treatment for RCC tumours 3-4cm
- surveillance
- ablative techniques
- partial nephrectomy
- radical nephrectomy
treatment for tumours over 7cm
radical nephrectomy
presentation of testicular cancer
- scrotal lump
- acute pain sometimes
what is found on examination of a cancerous testicle
- asymmetry or slight discolouration of scrotum
- hard, non-tender, irregular mass
investigations for testicular cancer
- USS
- CT chest abdomen for staging
- bloods
treatment for testicular cancer
- radical inguinal orchidectomy
- re check tumour markers 1 week post op
risk factors for penile cancer
- phimosis
- asia, africa, south america
- HPV
- smoking
- immunocompromised
treatment for penile cancer
- circumcision
- glans resurfacing
- glansectomy
- total penile amputation with formation of perineal urethrostomy