acid base balance physiology Flashcards
acidosis affect on CNS
depression of the CNS
alkalosis effect on CNS
over-excitability of the peripheral NS and later the CNS
what is hydrogen continually added from
- carbonic acid formation
- inorganic acids produced during breakdown of nutrients
- organic acids resulting from metabolism
what is the vast majority of hydrogen secretion used for
HCO3- reabsorption to prevent generation of acidosis
what does excretion of TA and ammonium do
simultaneously rids the body of acid load and regenerates buffer stores
what is compensation
the restoration of pH irrespective of what happens to HCO3- and PCO2
what is correction of an A-B disturbance
restoration of pH and HCO3- and PCO2 to normal
where does CO2 retention drive the equilibrium
to the right
why does HCO3- rise in respiratory acidosis
- as a result of the disorder
- as a result of the renal compensation
what drives hydrogen secretion by the kidney
blood pCO2
what does excessive removal of carbon dioxide do to hydrogen secretion into the tubule
reduces hydrogen secretion into the tubule
correction for metabolic alkalosis
- no TA or ammonium is generated
- HCO3- is excreted so then its levels fall back to normal
what compensates for respiratory acidosis/alkalosis
the renal system
-correction requires restoration of normal respiratory function
what compensates for metabolic acidosis/alkalosis
the respiratory system
-correction is made by the renal system
