Renal COPY Flashcards
Foam cells
Alport
Lumpy bumpy
Acute psgn
Focal mesangial proliferation
IgA nephropathy
Berger disease
Low c3 in
PSGN Lupus nephritis Bacterial endocarditis Shunt nephritis Visceral abscess
anterior lenticonus (extrusion of the central portion of the lens into the anterior chamber)
Alport
Compression of renal vein between aorta and superior mesenteric artery
Nutcracker syndrome
renin made in
juxtaglomerular apparatus
calcitriol made in
proximal tubule
primary site of antidiuretic hormone (vasopressin) response
collecting duct
erythropeitin secreted by
interstitial cells in medulla
cataract
intellectual disability
renal tubular acidosis
x linked recessive
Lowe syndrome
oculocerebrorenal syndrome
nephrotic proteinuria definition
> 40mg/m2/hr
or 1000mg/m2/day
or Up/Ucr >2.0
nephrotic syndrome
proteinuria >2g/m2/day
serum alb <3.og/dl
cholesterol >250mg/dl
edema
most common form nephrotic syndrome
minimal change
tubular proteinuria
tubular electrolyte wasting
glycosuria
fanconi syndrome
pathogens in peritonitis in nephrotic syndrome
strep
e coli
klebsiella
microangiopathic hemolytic anemia
thrombocytopenia
renal injury
hus
most common cause of ckd between birth and 10 years old
CAKUT
congenital anomalies of kidney and urinary tract
most common cause of ckd after 10 years old
focal segmental glomerulosclerosis
glomerulonephritis
advantage of radionuclide cystogram over voiding cystoureterogram
may detect more kids with mild VUR
less radiation
advantage of voiding cystoureterogram over radionuclide cystogram
additional anatomic detail
up to what grade of VUR surgery not warranted
I and II
classification VUR
I: nondilated ureter II: into pelvis and calyx (-) dilation III: mild to moderate dilation IV: moderate uretereal tortuosity V: gross dilation
autosomal recessive polycystic kidney disease due to gene defect
fibrocystin
most common inherited kidney disease
autosomal dominant polycystic kidney disease
autosomal dominant polycystic kidney disease due to gene defect
polycystin
most common cause of bladder outlet obstruction in males
posterior urethral valves
testicle swollen and tender
absent cremasteric reflex
testicular torsion
Protective glycoprotein secreted by tubules that inactive cytokines
Tamm Horsfall protein
Nephrotic syndrome definition
Proteinuria >3.5g/24 hrs
urine protein:Crea ratio >2
Hypoalbuminemia <2.5g/dL
Cholesterol >200mg/dL
Attainment of remission within 4 weeks of steroid therapy
Response
Sodium restriction
<1500mg/day
Early onset nephrotic
Progressive renal insufficiency
Ambiguous genitals
Wilms tumor
Denys drash syndrome
Treatment cystinosis
Cysteamine
Protienuria
Proximal rta
Glycosuria
Phosphaturia
Fanconi syndrome
Fair skinned Polyuria Phosphaturia Retinopathy Hypothyroidism Hepatosplenomegaly
Cystinosis
X linked disorder
Cataracts
Mental retardation
Fanconi syndrome
Oculocerebrorenal syndrome
Lowe syndrome
distal rta labs
Hypercalciuria Hypocitraturia Urine pH >5.5 HypoK Hyperchloremia Positive urine gap
Hypokalemic metabolic alkalosis
Hypercalciuria
Salt wasting
Bartter syndrome
muddy brown granular casts
acute tubular necrosis
hematuria 2-3 weeks after infection
psgn
hematuria 1-3 days after urti
igA nephropathy
arthritis, discoid rash, malar rash, photosensitivity, serositis
llupus nephritis
hempotysis
+ anti GBM antibodies
goodpasture syndrome
sinusitis
epistaxis
+ c ANCA
granulomatosis with polyangitis
wegener granulomatosis
lung involvement
+ p ANCA
microscopic polyangitis
sinusitis asthma skin findings eosinophilia \+ p ANCA
eosinophilic granulomatosis
Churg strauss
progressive loss of renal fxn in short time
crescents on renal biopsy
rapidly progressive glomerulonephritis
fever
eosinophilia
rash
UA + for eosinophils, WBC and RBC casts
allergic interstitial nephritis
bloody diarrhea anemia thrombocytopenia high LDH schitocytes
HUS
