Renal

Question 1

histo findings for post-strep glomerulonephritis

Answer 1

subepithelial humps

“lumpy bumpy” (IgG/IgM)

Question 2

histo findings for diffuse proliferative glomerulonephritis

Answer 2

wire looping

subENDOthelial humps (and sometimes intramembranous)

Question 3

histo findings IgA nephropathy

Answer 3

mesangial proliferation and immune complex deposition

Question 4

histo findings alport syndrome

Answer 4

thinning and splitting of GBM

Question 5

histo findings minimal change disease

Answer 5

normal

Question 6

histo findings focal segmental glomerulosclerosis

Answer 6

a segment of sclerosis in the glomerulus

Question 7

histo findings membranonephritis

Answer 7

thick glomerular filtration membrane

spike and dome appearance

subEPIthelial

Question 8

histo findings membranoproliferative glomerulonephritis type 1

Answer 8

“tram track”

subENDOthelial

Question 9

histo findings membranoproliferative glomerulonephritis type 2

Answer 9

intramembranous deposits

“dense deposit disease”

Question 10

presence of C3 nephritic factor indicates what dz process

Answer 10

membranoproliferative glomerulonephritis type 2

Question 11

histo diabetic nephropathy

Answer 11

non-enzymatic glycosylation of the glomerular basement membrane

hyaline arteriosclerosis

Question 12

histo for rapidly progressive glomerulonephritis

Answer 12

glomerular crescents

Question 13

IF goodpasture syndrome

Answer 13

linear IgG and C3 deposits

Question 14

IF post strep glomerulonephritis

Answer 14

granular deposits IgG and C3

Question 15

what are the types of rapidly progressive glomerulonephritis

Answer 15

• goodpasture
• microscopic polyangiitis
• wegener’s
• churg strauss

Question 16

what are the crescents made of in RPGN

Answer 16

firbin and macrophages