Equations Flashcards
flow rate
change in pressure/resistance
resistance
(8 x viscocity x length) / (pi x radius^4)
velocity
flow/cross sectional area
reynold’s number
(density x diameter x velocity) / viscocity
capacitance/compliance
volume/pressure
mean arterial pressure
(2/3 x diastolic) + (1/3 x systolic)
or
CO X TPR
stroke volume
EDV - ESV
pulse pressure
SBP - DBP
cardiac output
SV X HR
ejection fraction
SV/EDV
tension of vessel
(pressure x radius) / (2 x wall thickness)
clearance in kidney
(urine concentration x urine flow rate) / plasma concentration
effective renal plasma flow
urine concentration of PAH x (urine flow / plasma concentration of PAH)
renal blood flow
renal plasma flow / (1- Hct)
filtered load in kidney
GFR x plasma concentration
excretion rate in kidney
urine flow x urine concentration
osmolarity
(2 x Na) + (glucose/18) + (BUN/2.8)
GFR
KF [(glomerular capillary hydrostatic pressure - bowman space hydrostatic pressure) - (glomerular capillary oncotic pressure - bowman space oncotic pressure)]
*bowman space oncotic pressure is assumed to be 0
or
GFR = urine concentration of inulin x (urine flow rate/plasma concentration of inulin)
plasma volume
total body volume x (1 - Hct)
filtered fraction
GFR/RPF
volume of distribution
amount of drug in body/plasma drug concentration
clearance of drug
rate of elimination of drug/plasma drug concentration
loading dose
(target plasma concentration at steady state x volume of distribution) / bioavailability
maintenance dose
(target plasma concentration at steady state x clearance x dosage interval) / bioavailability
therapeutic index
median toxic dose/median effective dose