Renal 5th

Question 1

Macula densa pathway

increase angiotensin II

Increase calcium

____________renin

Answer 1

decrease renin if there is an increase in angiotensin II

Question 2

Active renin release is controlled by the
a renal vascular receptor, macula densa, the
_________________, and negative
feedback by Ang II

Answer 2

macula densa

sympathetic nervous system

Question 3

β-Adrenergic receptor pathway
Norepinephrine

Activated B1 receptor by catecholamines (Norephedrine)

Increase in cAMP

leads to a ________ in renin

Answer 3

increase

Question 4

Which of the following causes
vasodilation? Select all that apply

NO (nitric oxide) and prostaglandins

Question 5

increase in cAMP means a _______ in renin release

Answer 5

increase

Question 6

Increase in calcium means ______in renin release

Answer 6

decrease

Question 7

decrease in camp means a _______in renin release

Answer 7

decrease

Question 8

Baroreceptor pathway

Increase BP leads to what? ___________of renin release

Answer 8

inhibition

Question 9

Baroreceptor pathway

Decrease BP leads to what? _________of renin release

Answer 9

stimulation

Question 10

Macula densa pathway

NaCl transport increase does what to renin release?

By ATP release
By Adenosine (ADO) release

Answer 10

inhibits renin release

Question 11

Macula densa pathway

NaCl transport decreases does what to renin release?

PGE2 and PGI2:increase cAMP
Nitric Oxide (NO): increase cAMP

Answer 11

stimulates renin release

Question 12

Ang II → Negative Feedback →__________renin release

Answer 12

inhibits

Question 13

β-Adrenergic receptor pathway

β1 adrenoceptor activation: ____________ of renin release

Answer 13

stimulation

Question 14

Low BP → low GFR → low Urine (True/False)

Question 15

Low BP stimulates (A. parasympathetic, B. sympathetic)
nervous system to release Norepinephrine.

Question 16

Beta1 adrenoceptors (A. decrease, B. increase) Heart Rate.

Question 17

Activated (A. alpha1 adrenoceptor, B. beta1 adrenoceptor)
in juxtaglomerular cells leads to renin secretion.

Question 18

Activated (A. alpha1 adrenoceptor,B. beta1 adrenoceptor)
in afferent arterioles leads to vasoconstriction.

Question 19

Prostanoid biosynthesis

Major renal eicosanoid products are PGE2 and PGI2

Question 20

Renal PGE2 and PGI2

Local Effects

Afferent Arteriolar Vasodilation:
Increases with reduced renal blood flow (RBF).

Question 21

NSAIDs

increased vasoconstriction, and ____________ GFR.

Answer 21

reduced