Renal Flashcards
__________ – Detoxing the blood using energy
20-25% of the cardiac output at rest
7-10% of total-body O2 intake
Kidney
Functions of the Kidneys
- Excretion
2.Homeostatic functions
3.___________functions
Endocrine
Excretion of wastes
Filtration–>___________/Secretion—>
Reabsorption
Excretion
Urine formation
Nitrogenous wastes
_________,ammonia from amino acids
__________from creatine phosphate
__________from nucleic acids
Foreign substances (drugs, environmental toxins)
urea
Creatinine
Uric acid
Regulation of blood ionic composition
Control blood ________ levels by adjusting the excretion of ions in urine
Sodium ions (Na+)
Potassium ions (K+)
Calcium ions (Ca2+)
Chloride ions (Cl−)
Phosphate ions (HPO42−)
ion levels
Regulation of blood pH
Excrete a variable amount of __________ ions (H+) into the urine
Conserve ____________ ions (HCO3−), an important buffer of H+ in the blood
NH4+ regulation
hydrogen ions
bicarbonate
Kidney does Regulation of blood volume
Adjust blood volume by conserving or eliminating
water in the urine.
An increase in blood volume (BV)
increases blood pressure (BP)
A decrease in blood volume (BV)
decreases blood pressure (BP)
Regulation of Blood Pressure
Regulate blood pressure by secreting the
enzyme __________
Renin–Angiotensin–Aldosterone System
(RAAS)
Increased renin → _________ in BP
renin
Increase
Production of hormones
______________
Production of RBCs
Erythropoietin
Production of hormones
_____________
Active form of vitamin D
Calcium homeostasis
Calcitriol
Kidney’s function : Maintenance of Blood Osmolarity
Maintain a blood osmolarity 300 milliosmoles per liter (mOsm/liter) ___________
Anti-Diuretic Hormone
Kidneys function:
Regulation of blood glucose level
Use the glutamine in gluconeogenesis
→ release glucose into the blood
_________ - Functional units of the kidney
Nephron
Renal corpuscle
= ______________
+ Glomerulus
glomerular capsule
The primary site of urine concentration?
A. Juxtamedullary nephrons
B. Cortical nephrons
A. Juxtamedullary nephrons
Renal Circulation
Renal artery
→→→ Afferent arteriole → __________ → Efferent arteriole
→ ___________/Vasa recta
→→→ Renal vein
glomerulus
peritubular capillaries
Nephron tubule covered by peritubular capillaries and vasa recta
Blood enters and leaves glomerular capillaries at high pressure, causing fluid to ________ the tubule.
The peritubular network _______ filtered fluid from the tubular lumen.
filter into
reabsorbs