Renal Flashcards

1
Q

Renal structures

A
kidney
Calyx
Renal pelivs
Ureters
Urinary bladder 
Urethra
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2
Q

Important renal function

A
Remove waste from blood and regulate blood bol(BP)
Renal corpuscle=filter blood
Tubules=filter travel here
-recover ion/H2O
  :change osmo.
  :conc. Urine
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3
Q

Kidney organ: Capsule–> renal papilla

A

Capsule
Cortex
Medullan

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4
Q

Capsule

A
Cover cortex 
Not serosa/adventitia 
Outter layer=dense CT (humans)
Inner layer=collagen 
-myoepithlium cell=all for little contraction when in needn
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5
Q

Medulla

A

Archeite BV=leg BV b/w medulla/cortex junction junction
Medullar rays= start at cortex and end in medulla
-ie lobe
Projection ion=papilla causing creates open (ie minor caylex)

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6
Q

Cortex

A

Renal corpuscle=glomurulous

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7
Q

Fluid flow

A
Glom/glom. Memb.
PCT
PST
LOH
DST
DCT
Collecting tube 
Duct of berline
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8
Q

Glomerulus

A
Initial filtrate
-across memb.
- kidney produce 125ml/min. 
  :124 reabsorb.
  :1 ml. Produce 
Plasma in cap. Is exudate into urinary space 
Tuft cap. in renal corpuscle
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9
Q

Renal corpuscle

A

Glomerulus(cap.) and bowman’s capsule (parietal epith.=simple Sq. w/ podocyte step. urinary space)
Other structures
-vascular cap.=aff./eff. Arteriole
-macula densa/JG cell=erg. Cells
-mesangial(w/in glom.) and extraglom. mesangial cells(Lasix/outside glom.)=supporting cell
-podocyte=surrounding cap.
-visceral layer bowmans cap.

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10
Q

Glom. Memb.

A
Across memb.=filtration 
Reg. plasma move into urinary space 
Structures 
-endoth. (cytop)
-fenestration
-basal lamina=from podocyte and endoth. 
-pedicles=podocyte foot process 
  :b/w filtration slit 
-podocyte=wraparound cap
  :from BC visceral layer 
  :primary-->secondary-->pedicle(interdegitate each other)
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11
Q

Across glom memb.

A

~ to plasma w/ ion conc. And w/o macromolec.
No prot. >70kda to pass (albumin)
A lot of proteoglycan has neg. =restricts movement of positive

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12
Q

Fluid flow that is conc.

A
PCT
PST
LOH
DST
DCT
Collecting duct
Duct of berlin
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13
Q

PCT

A
Incre. Mitoch/microvilli for active transport for ion transportation 
Histology 
-simp. Cuboidal 
-visible BB/ not clean boarders 
-incr. eosin b/c mitoch.
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14
Q

PST

A

Na/organic acid

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15
Q

LOH

A
Ion recovery/excrete H2O
Structure 
-Thin descending=excrete H2O/influx ion 
-Thin ascending=excrete ion 
-thick ascending=ion efflux
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16
Q

DST

A

ATP=K/Na

H/bicarb.

17
Q

DCT

A
Excrete H2O
Reg. blood from renal cap. 
Histo.
-simp. Cubo. 
-decre. eosin b/c decre. mitoch./BB
18
Q

Collecting duct

A

W/ in cortex and medulla

-ie medullary rays

19
Q

Duct of berlin

A

Medullary duct
In the area of cabrosa
Lrg duct

20
Q

BP reg. By

A

Elevate arteriole P by incre. eff. P

Decre. arteriole P by decre. Aff. P

21
Q

Inctre. Afferent arteriole P

A

Incre. Eff. P=incre. Cap.=incre. GFR
-change iconic conc. and decre. Na/Cl recovery
Macula densa detects an incre. Na/Cl
-release vasoactive to constrict aff. arteriole
-decre. GFR
-decre. Na/Cl

22
Q

Decre. Aff. arteriole P

A
\+ juxtaglom. cells =modified sm. Muscle 
-release renin (asparty protease) cleaves angiotensinogen form angiotensin I
Lung cap. ACE convert I-->amigo. II
Incre. BP stop renin release 
-temp not chronic
23
Q

Anigo.II

A

Vasoconstrict.= incre. BP
+ adrenal glands release aldosterone
-+ Na/H2O absorb.
-incre. Vol. /incre. P by sm. Muscle BV

24
Q

Urinary exit

A

Urine collected= area cribrosa
Ureters
Bladder
Urethra

25
Q

Urine collection

A
From tubules= area cabrosa
Collecting tubules join=duct
Lrg. Duct enter renal papilla
Empty-->minor calyx 
-lined w/ urothelium 
-pore w/ lrg collecting duct minot calyx 
  :pore=ducts of Berlin
26
Q

Ureters

A
Muscle tubules lined with urothelium 
Urine drains from urothelium 
Info. 
-2
-exit renal pelvis (@hilum)
-enters bladder @oblique angle 
  :post surface 
  : Adv. Not urine back flow liq. Press on ureters 
  :orientation/seal tubes 
-wall
  :urothelium 
  :loose CT
  :muscularis (sm. Muscle)
    *inner longitudinal 
    *middle circular 
    *outer longitudinal/distal end 
  :adventitia
27
Q

Bladder

A
Muscle sac-like organ lined w/ urothelium 
Store urine in pelvis 
2 uretic orifices w/ 1 internal urethric orifices 
-posterior 
Wall
-urothelium 
-loose CT
-dense irreg. CT
-muscularis 
  :3 sm. Muscle layers 
  :irreg. Arrange 
-seroa/adventitia
28
Q

Urethra

A
Male
-terminal duct for urinary/reproductive 
-3 set. 
  :prostatic (bladder neck through prostate) 
  :memb.(to penis bulb)
  :spongy(penile)
    *glands in wall 
-epith.
  :urothelium(prostatic) 
  :psedostr. (memb.)
  :SSE(spongy)
Female 
-shorter than male 
-urothelium=SSE
29
Q

Urothelium

A
Ie: Transitional epith. 
Only in urinary tract 
Stretches=cells move pass each other during destention 
-few layers 
-umbrella cellmappear smaller/flatter