Esophagus/stomach Flashcards
Mucosa components for esohpagus
St. sq. non. keratinze
Lp=loose CT w/ immune cells
Musculris muscle=thin layer of sm. muscle
Submucosa component
Dense CT w/ lrg. BV/GLAND
Meissner plexus=gastro intestinal gang.
Muscular externa layers and middle N.
circular inner
plexus of auerbach (middle)
-AKA meinteric plexus
longitudinal outer
Serosa vs. adventia layer
Serosa=sm. sq. epith. -overlying CT Adventia=dense CT -lrg. BV/lymph. -adipose
Esophagus-mucosa components
Epith.=St. sq. non. kert.
-R abrasion from food (also have help w/ mucous gland and saliva)
LP=loose CT w/ immune
-muscularis sep. w/ rest of mucousa and submucosa
BOTH secrete mucous for food movement and bicarb to counteract acid
Esophagus-2 glands
Esophageal cardiac gland
Esophageal gland proper
Esophageal cardiac glands
W/in LP closer to cardiac
Esophageal gland proper
in submucosa closer to oral cavity
under muscularis mucosa and submucosal CT W/ BV/N
Esophageal-muscle externa
2 muscle layers beneath the submucosa
Upper 1/3=sk. muscle (near pharynx)
Mid 1/3=sk. and sm. muscle
Lower 1/3=sm. muscle (near stomach)
Enteric gang. ASSOC w/ which layer of GIT
Muscularis externa
Enteric gang. location
Meisners plexus=submucosa
Myenteric Auerbach plexus=b/w 2 layers of muscularis externa
Esophageal-serosa or adventitia content
Dense CT, adipose lrg BV/lynph
Sep. esophagus from lung.
Does the stomach’s muscularis externa have 2 or 3 layers?
3 layers w/ different orientation
how does stomach disassemble food and epith.?
Disassemble=acid/enzymes
Sim. columnar epith.
-surface mucous cells
Stomach organization
Lower esophageal spincter=sm. muscle Cardiac Fundic=main body -main acid production -ruggae=folding of mucosa/submucosa :submucosa, muscularis mucosa/submucosa (physical apperance b/c glandular tissue) Pyloric Pyloric sphincter=sm. muscle sep. stomach from intestine
Glandular tissue found throughout the stomach?
Yes
Grow down into LP
Section portion of glandular tissue
Gastric pit=duct -has surface mucous cells Neck -shorter columnar cell w/ smaller mucous cap -mucous neck cell Secretory=gastric gland
Diff. sizes of glands throughout the stomach
Cardiac=pit/scretory same size
Fundic=larger glands than pit
Pyloric=larger pit than glands
Fundic mucosa
Light zone -closer to mouth -narrow -Thin and adoral Dark zone -farther from mouth -wide -darker and aboral
mucous produce in stomach
surface mucous cell
Surface mucous cell
Protect
Akaline(bicarb.)=R to stomach acid
Mucin product combines to H2O
-gel like production coating epith. cell/protect from acid
Mucous dnt fully protect cells but incre. cell turnover
Mitoch. w/ carbonic anhydrase contribute to form bicarb.
Pyloric and cardiac gland secrete
Mostly mucous/lysozyme (antibact.)
Bicarb. a biproduct of acid production?
Yes
Cell found w/in gastric glands
All are mainly found in the fundic
Chief Cells
Parital cells
Enteroendocrine cell(throughout the stomach)
Chief cells
Found deeper in the gland Pepsin enzyme -Pepsinogen(inactive) found w/in zymogen granules Travles: gland-->lumen-->stomach by merocrine method Inre. RER for protein production Histo. -basal nuclei -granules @ surface -deeper in gland
Parital cells
Found further up in the gland
Tubercle vesicle
Secretory caniculi=location of stomach acid production
-CO2 +H2O–>bicarb(blood and mucous cell) and H+
-NaCl=Cl import
-K+ help balance the ion import
-Caniculi=H+ +Cl–>HCl
Also create intrinsic factor (IF) for vit. B12
Enteroendocrine
Produce hormones
Deep in gland
HIsto.
-clear cytoplasm w/ nuceuls off center
