Renal Flashcards

1
Q

involuntary urination in children >4yo

A

enuresis

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2
Q

high BUN & creatinine

A

azotemia

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3
Q

swelling of one or both kidneys

A

hydronephrosis

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4
Q

GFR requiring adjustment of med dosages

GFR requiring dialysis

A

60

10-15

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5
Q

URINARY TRACT OBSTRUCTION

explanation

etiology

s/s

dx test

A
  • Blockage that inhibits flow of urine through normal pathway
  • Etiology - urolithiasis; BPH; tumor
  • s/s - fever; n/v; flank pain; difficulty starting stream; limited urine; hydronephrosis
  • Blunt percussion to the kidney causing pain indicates hydronephrosis
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6
Q

RENAL CALCULI

explanation

etiology & types

r/f

s/s

complication

A
  • Urolithiasis - usually made of calcium or uric acid (also struvite, crystalline) - form inside kidney & can travel through UT
  • Etiology - varies on type
    • Struvite - infection
    • Uric acid - gout
  • r/f - dietary; infection; ↑ uric acid; genetics
  • s/s - hydronephrosis; unilateral flank pain; n/v; retching with waves of pain; dysuria; hematuria; frequency with small voids; hesitancy
  • More painful & complicated if stone gets stuck in ureter
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7
Q

CYSTITIS

etiology

r/f

s/s

A
  • “UTI” or “bladder infection”
  • Etiology - usually E. coli
  • r/f - aging (loss of estrogen, skin changes around vulva); young girls; female; Foley; incontinence; sexual activity
  • s/s - dysuria; frequency; hematuria; cloudy urine; malodorous urine; confusion in older pts
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8
Q

PYELONEPHRITIS

etiology

r/f

s/s

A
  • “Kidney infection”
  • Etiology - often ascends from bladder; usually E. coli
  • r/f - frequent UTI; reflux; catheter use; enlarged prostate; CKD; kidney stones; DM; immunocompromise
  • s/s - systemic - fever; n/v; malaise; colicky flank pain, waves of nausea; chills; dysuria (burning with urination); malodorous urine; hematuria; urgency; frequency; pyuria
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9
Q

STRESS INCONTINENCE

explanation

etiology

r/f

s/s

A
  • Physical activity puts pressure on bladder
  • Etiology - sphincter & pelvic muscles are stretched out and weak
  • r/f - pregnancy; childbirth; obesity
  • s/s - loss of urine with standing up, laughing, coughing, sneezing, lifting, sex, exercise
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10
Q

OVERFLOW INCONTINENCE

explanation

etiology

r/f

s/s

A
  • Overfull bladder
  • Etiology - nerve damage affecting ability to sense fullness; blockage in urinary tract; weak detrusor muscle; medications
  • r/f - enlarged prostate; kidney stones; neurological damage; tumors; DM; MS; trauma
  • s/s - leaking urine without sensation of fullness__, with full bladder
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11
Q

URINARY RETENTION

explanation

etiology

r/f

s/s

A
  • Inability to completely empty bladder
  • Etiology - nerve damage affecting ability to sense fullness; blockage in urinary tract; weak detrusor muscle
  • r/f - recent surgery, especially to bladder; neurological damage; blockage; structural
  • s/s - inability to empty bladder despite fullness
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12
Q

NEPHROTIC SYNDROME

explanation

etiology

r/f

s/s

A
  • Too much protein excretion
  • Etiology - damage to basement membrane - ↑ permeability of capillary wall
  • r/f - infection; CKD; DM; lupus; medications
  • s/s - proteinuria; edema; foamy urine; wt gain, ascites, puffy face (fluid leaving vascular compartment); fatigue; loss of appetite; hypoalbuminemia; HLD (liver’s response to hypoalbuminemia); ↓ antithrombin 3 (hypercoagulative state)
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13
Q

GLOMERULONEPHRITIS - NEPHRITIC SYNDROME

explanation

etiology

r/f

s/s

A
  • Inflammation of glomerulus; Damage to basement membrane - larger molecules (RBCs, WBCs) able to enter filtrate
  • Etiology - autoimmune, type 3 hypersensitivity - complexes get stuck in glomerulus & cause damage
  • r/f - infection; immune disease; vasculitis; DM; HTN
  • s/s - severe hematuria (cola colored)__; pyuria__; proteinuria; edema; HTN; oliguria
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14
Q

3 types of acute kidney injury

A
  • Prerenal - blood flow to kidney
  • Intrarenal - within kidney
  • Postrenal - ureters, bladder, urethra
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15
Q

PRERENAL AKI

etiology

r/f

s/s

A
  • Sudden renal hypoperfusion
  • r/f - hemorrhage/blood loss__; HF; sepsis; severe dehydration; severe burns; pancreatitis; hepatitis; blood loss in surgery, injury
  • s/s - hypovolemia; thirst; ↓ urine; dizziness; ortho hypotension; v/d; hemorrhage
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16
Q

INTRARENAL AKI

etiology

r/f

s/s

A
  • Sudden episode of kidney failure due to direct glomerular damage
  • r/f - infection; chronic disease (GN, nephrotic syndrome); toxins; medications
  • s/s - vary - fever; rash; hematuria; oliguria; fatigue; dyspnea; nausea
17
Q

POSTRENAL AKI

etiology

A
  • Sudden episode of kidney failure - blockage below kidneys causes waste to back up
  • Etiology - varies - tumor; enlarged prostate; stone
18
Q

9th leading cause of death in US

A

CKD

19
Q

gradual, progressive loss of kidney function

A

chronic kidney disease/renal failure

20
Q

stages of renal failure with % kidney function

A
  • 1 - 90% or more function
  • 2 - 60-89%
  • 3 - 30-59%
  • 4 - 15-29%
  • 5 - <15% - end stage renal failure
21
Q

etiology of CKD

A

increasing amount of glomerular damage, leading to kidneys’ inability to manage filtration

  • Acute bil kidney diseases
  • Severe, prolonged circulatory shock/HF
  • Nephrotoxins
  • Mechanical obstruction
22
Q

r/f for CKD

A

DM; HTN; CV disease; older age; Native American; African American; smoking; obesity; abnormal kidney; family hx

23
Q

urinary sx of CKD

A

↓ urine output

azotemia

24
Q

neuro sx of CKD

A

anxiety

depression

fatigue

h/a

sleep disturbance

encephalopathy

peripheral neuropathy

25
Q

CV sx of CKD

A

HTN

HF

CAD

pericarditis

PAD

anemia (↓ erythropoietin)

bleeding

26
Q

ocular sx of CKD

A

hypertensive retinopathy

27
Q

GI sx of CKD

A

anorexia

n/v

bleeding

gastritis

28
Q

respiratory sx of CKD

A

pulmonary edema

uremic pleuritis

pneumonia

29
Q

endo/reproductive sx of CKD

A

hyperparathyroidism

thyroid abnormalities

amenorrhea

ED

30
Q

integ sx of CKD

A

pruritus (azotemia)

ecchymosis

dry, scaly skin

31
Q

metabolic sx of CKD

A

carbohydrate intolerance

HLD

32
Q

MS sx of CKD

A

calcifications

osteomalacia

33
Q

HEMODIALYSIS

function

accessed how?

performed when?

A
  • Filters wastes and water from blood
  • Helps control BP, balance K, Na, Ca
  • Vascular access - ONLY use for dialysis
    • Arteriovenous (AV) fistula
    • AV graft
    • Catheter
  • 3x/week for 4 hours
34
Q

PERITONEAL DIALYSIS

uses what?

how to use?

accessed how?

A
  • Uses peritoneum to filter blood
  • Must empty used solution & refill with fresh solution 4-6x/day
  • Surgical catheter placement
35
Q

BLADDER CANCER

prevalence

r/f

s/s

prognosis

A
  • Very common cancer
  • r/f - smoking; older age; male; exposure to toxins; parasitic infections
  • s/s - hematuria; dysuria; back pain; pelvic pain; frequency
  • Prognosis - >77% survive 5 years