Red Cell Disorders (REVISE) Flashcards
What percentage of anaemias are from iron deficiency
95%
Is diet a significant cause of anaemia
No it is very rarely a cause
Different types of anaemias
Iron deficiency anaemia Megaloblastic anaemia Haemolytic anaemia Aplastic anaemia Sickle cell Thalassaemias
Symptoms of Anaemia
Shortness of breath
Weakness/Lethargy
Tachycardia
Does skin colour (not race; literal colour) indicate anaemia; what else/alternative
Skin colour not a reliable sign, as this is determined by blood flow. Nail bed and conjunctiva may be pale
What might severe anaemia cause in elderly
Angina
Oral manifestations of anaemia (REVISE)
Glossitis (painful red tongue)
Angular cheilitis (fissures at corner of mouth)
How might DPG levels change in anaemic patients
DPG may be elevated in RBCs so O2 more readily given up to tissues
Microcytic Anaemia
Anaemia caused by decreased MCV; type of iron deficiency
Why does iron deficiency anaemia cause microcytic anaemia
Body is starved of iron so RBCs are abnormally small as one of their main components is depleted
Label
Usual treatment for Iron Deficiency Anaemia
Usually Iron Sulfate (FeSO4)
Find and treat the underlying cause (e.g. GI Bleeding, menstrual problems)
REVISE
Normocytic Anaemia
Patient has normal-sized red blood cells, but a low number of them
Renal Anaemia
Kidney produces EPO, so in chronic kidney disease, RBC production is not stimulated which causes normocytic anaemia
REVISE MINORLY
How do pregnancies affect anaemia
Dilution and/or iron deficiency as the foetus is taking iron from the mother
Hormones of pregnancy increase MCV while iron reduces it causing normocytic anaemia
REVISE MINORLY JUST DOUBLE CHECK