QUIZ I Intro to Oral Biology Flashcards

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1
Q

what is the craniofacial complex?

A

head, face, and neck

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2
Q

in order to properly diagnose, prognosticate, treat, and evaluate dental diseases and disorders, we must fully understand what?

A

how normal tissues develop and function

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3
Q

what makes up the dentition?

A
  • teeth
  • enamel
  • dentin
  • cementum
  • bone
  • periodontal ligament
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4
Q

describe teeth

A
  • occupy 20% surface area in the oral cavity
  • masticatory force 500-700 newtons/ 110-160 lbs of force
  • mastication, speech, esthetics, defense, bone health
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5
Q

describe enamel

A
  • 96% mineral
  • non-vital
  • brittle
  • ameloblasts
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6
Q

describe dentin

A
  • ~70% mineral
  • elastic
  • permeable
  • vital
  • odontoblasts
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7
Q

describe cementum

A
  • 50% mineral
  • thin
  • vital
  • attachment site
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8
Q

describe bone

A
  • 50% mineral
  • support
  • remodels continually
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9
Q

describe the periodontal ligament

A
  • hammock
  • fibrous
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10
Q

what 3 features form the periodontium?

A

cementum, bone, and periodontal ligament

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11
Q

what is the clinical crown?

A

the visible portion of the crown that is not covered by gingival tissues

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12
Q

what is the anatomic crown?

A

the entire part of the crown covered in enamel (it is usually larger than the clinical crown in a healthy mouth)

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13
Q

describe finding disease genes

A

nucleus → chromosome → band → gene → mutation

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14
Q

describe approaches to identifying disease susceptibility genes

A
  • linkage analysis
    • studies families with more than one affected individual
  • candidate gene analysis (association study)
    • compares people with the disease to people with the disorder
    • case-control
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15
Q

what are 2 forms of genetic variation?

A

mutation and polymorphism

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16
Q

what is a mutation?

A
  • rare change in the DNA sequence
  • refers to negative effect
  • a form of polymorphism
17
Q

what is a polymorphism?

A
  • 2 or more alleles in the population
  • may be benign or predispose to disease
  • present in 1% of the population
18
Q

what are 4 types of mutations?

A
  • point mutation
  • deletion
  • insertion
  • frame shift
19
Q

what are the 4 main stages in tooth development?

A
  1. initiation
  2. morphogenesis
  3. dentin and enamel deposition
  4. tooth formation and eruption

dental lamina (mesenchyme and ectoderm) → bud → cap → bell → tooth

20
Q

what is tooth agenesis?

A

congenitally missing teeth

21
Q

what is cleidocranial dysplasia?

A

a condition in which a third layer of teeth is formed

22
Q

what are 4 clinical correlates of enamel?

A
  • genetic disorders
  • fluorosis
  • febrile/tetracycline use
  • dental caries
23
Q

what are the dentin and pulp cells?

A

odontoblasts

24
Q

what are 2 clinical correlates of the dentin-pulp complex?

A

genetic disorders and dental caries

25
Q

what are 5 types of dentin?

A
  • predentin
  • primary dentin
  • secondary dentin
  • tertiary dentin
  • mantle dentin
26
Q

what are 5 challenges of modulating inflammation?

A
  • infected pulp tissue
  • inflamed pulp tissue
  • decay
  • abscess
  • inflamed ligament
27
Q

name the 6 principal fiber groups within the periodontium

A
  • transseptal ligament
  • alveolar crest group
  • horizontal group
  • oblique group
  • apical group
  • interradicular group