QUIZ 2 Embryology of the Head, Face, and Oral Cavity Flashcards

1
Q

orofacial development begins at ___ weeks in utero

A

4

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2
Q

once the olfactory placodes develop, what happens?

A

ectomesenchyme proliferates on both sides of each placode, resulting in medial and lateral nasal processes

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3
Q

what merges to form the upper lip?

A

medial nasal processes merge with each other, as well as the maxillary processes of the first branchial arches

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4
Q

upper lip formation occurs from weeks ___ to ___

A

6-7

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5
Q

what merges to form the primary palate?

A

medial nasal process

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6
Q

the secondary palate is formed from the ___ processes of the first ___ arches

A
  • maxillary
  • branchial
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7
Q

what makes up 90% of the hard and soft palates?

A

secondary palate

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8
Q

what are the developmental conditions that can affect orofacial development?

A
  • developmental
    • anomaly of development
  • hereditary/genetic
    • familial - runs in families
    • congenital - present at birth
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9
Q

a cleft lip is the result of the defective fusion of which two processes?

A

medial nasal process and the maxillary process

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10
Q

what percent of cleft lip cases are unilateral?

A

80%

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11
Q

cleft palate is the failure of what to fuse?

A

the palatal shelves

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12
Q

the minimal manifestation of cleft palate is a ___

A

bifid uvula

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13
Q

describe treatment of cleft lip

A

rule of 10

  • 10 weeks old
  • 10 lbs
  • 10 grams % hemoglobin
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14
Q

describe treatment of cleft palate

A

about 1 1/2 years

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15
Q

what % of orofacial clefts are cleft lip and palate?

A

45%

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16
Q

what % of orofacial clefts are cleft palate only?

17
Q

what % of orofacial clefts are cleft lip only?

18
Q

what percent of syndromic patients have cleft lip AND cleft palate?

19
Q

what percent of syndromic patients have cleft palate only?

20
Q

describe Pierre Robin sequence

A
  • cleft palate
  • mandibular micrognathia
  • glossoptosis (downward displacement of the tongue)
21
Q

describe environmental factors of nonsyndromic clefts

A
  • maternal alcohol or cigarette use
  • folic acid deficiency
  • corticosteroid use
  • anticonvulsant therapy
22
Q

what type of cleft is described as a lack of fusion of the maxillary and mandibular processes?

A

lateral facial cleft

23
Q

what type of cleft is described as failure of fusion of the lateral nasal processes with maxillary process?

A

oblique facial cleft

24
Q

what type of cleft is described as failure of fusion of the medial nasal processes?

A

median cleft of the upper lip

25
what type of cleft is more common in males?
CL + CP
26
what type of cleft is more common in females?
cleft palate only
27
describe the prevalence of orofacial clefts among native americans, asians, caucasians, and african americans
* native americans: 1/250 * asians: 1/300 * caucasians: 1/700 * african americans: 1/1500
28
how can a submucous palatal cleft develop?
* surface is intact, but defect exists in the underlying musculature of the soft palate * epithelium seals off cleft, but bones are still separated * a bone notch will be present on the posterior hard palate margin * appears as a bluish midline discoloration
29
name the 9 individuals that can be involved in management of orofacial clefts
* pediatrician * OMFS * ENT * plastic surgeon * pediatric dentist * orthodontist * prosthodontist * speech pathologist * geneticist
30
describe commissural lip pits
* angle of the mouth * mucosal invaginations that occur at the corners of the mouth on the vermillion border * not associated with facial or palatal clefts
31
describe paramedian lip pits
* congenital invaginations of the lower lip * usually bilaterally located * no treatment except evaluate for syndrome
32
describe van der woude syndrome
* greatest significance of paramedian lip pits * cleft lip and cleft palate * most common form of syndromic clefting
33
what is microglossia?
* abnormally small tongue * usually syndromic
34
what is aglossia?
missing tongue
35
microglossia is frequently associated with what?
hypoplasia of the mandible
36
what may be missing in microglossia?
lower incisors
37
what is ankyloglossia?
developmental tongue abnormality characterized by a short, thick lingual frenum resulting in limitation of tongue movement aka tongue tied
38
akyloglossia may cause problems with what?
speech and breastfeeding
39
what are the treatment options for ankyloglossia?
frenotomy or frenuloplasty around age 4-5