QuesMed Errors Flashcards
1
Q
Mechanism of Action of Bosentan.
A
Endothelin-A Receptor Antagonist, preventing vasoconstriction of smooth muscles in pulmonary vessels.
2
Q
Caution of Bosentan.
A
Monitor LFTs - can cause deranged LFTs and contraindicated in moderate-severe hepatic impairment.
3
Q
Give a UTI antibiotic that may (rarely) cause pulmonary fibrosis.
A
Nitrofurantoin.
4
Q
What ECG abnormality can be seen most commonly in PEs?
A
Sinus Tachycardia (increased sympathetic flow to maintain CO) with Right Ventricular Strain (High Pulmonary Artery Pressures).