Q3 Psychopharmacology 2 Flashcards
what is the medical term for twisted neck
- torticollis
what is the medical term for prolonged involuntary upward deviation of the eyes
- oculogyric crisis
what is the medical term for head drawn back, either due to a spasmodic contracture
- retrocollois
what is the medical term for spasm of the vocal cords that makes it difficult to speak or breathe
- laryngospasm
what is the benefit of 5HT2A antagonism in second generation antipsychotics
what is the side effect
- mitigates movement adverse effects
- develops metabolic syndrome
who does acute dystonia affect
- young
- african american
- male
when does acute dystonia occur
- 3-5 days later
treatment for acute dystonia
- anti-cholinergic
who does pseudoparkinsonism affect
- elderly
- caucasian
- women
when does psuedoparkinsonism occur
- first month after initiation
treatment for psuedoparkinsonism
- reduce dose
- anticholinergic
when does akathisia occur
- first 3 months
what is akathisia
- movement disorder that makes it hard for you to stay still
treatment for akathisia
- reduce dose
- benzo
- beta blocker
when does tardive dyskinesia begin
- after 3 months
treatment for tardive dyskinesia
- stop anticholinergics
- switch to clozapine or lower dose
important lab finding of neuroleptic malignant syndrome
- elevated serum CK
- rhabdomyolysis
clozapine used for
- refractory schizophrenia
side effects of clozapine
- agranulocytosis
- myocarditis
- seizures
- small bowel obstruction
- metabolic syndrome
hyperprolactinemia is highest with which drugs
- risperidone
- palliperidone
MOA of aripiprazole
important side effect
- partial DA receptor agonist
- akathisia
side effects of guanfacine (alpha 2 agonist)
- hypotension
- sedation
side effects of clonidine (alpha 2 agonist)
- headache
- xerostoma
benzodiazepines that have less hepatotoxic issues
- oxazepam
- temazepam
- lorazepam
symptoms of buspirone toxicity
- headache
- activation (nervousness or excitement)