Pulmonary Vascular Disease Flashcards

1
Q

Pulmonary embolism

A

Thrombus forms in the venous system and embolisms to the pulmonary arteries

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2
Q

Major risk factors of PE

A
Recent major trauma
Recent surgery
Cancer
Significant cardiopulmonary disease
Pregnancy 
Inherited thrombophilia
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3
Q

Symptoms of PE

A
Pleuritic chest pain
Cough
Haemoptysis
Isolated acute dyspnoea (multiple)
Syncope or cardiac arrest (massive)
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4
Q

Signs of PE

A
Preyxia 
Pleural rub (walking in snow)
Stony dullness to percussion at base (effusion)
Tachycardia, tachypnoea, hypoxia
Hypotension
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5
Q

PE investigations

A
FBC, biochemistry troponin 1, blood gases
Chest x-ray
ECG
D-dimer
CT pulmonary angiogram
V/Q scan
Echocardiography
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6
Q

Prognosis of PE based on

A

Age
Sex
Comorbidity
Physiological parameters

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7
Q

PE treatment

A
Oxygen
Low molecular weight heparin
Direct oral anticoagulants - rivaroxaban, apixaban
Thrombolysis - alteplase 
Pulmonary embolectomy
Warfarin - anticoagulant
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8
Q

Pulmonary hypertension

A

Elevated blood pressure in pulmonary arterial tree

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9
Q

Pulmonary hypertension when pulmonary pressure greater than

A

25mmHg

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10
Q

Idiopathic pulmonary hypertension epidemiology

A

Young people
Rare
Can be fatal

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11
Q

Secondary pulmonary hypertension epidemiology

A

Older people
More common
Not usually fatal

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12
Q

Causes of hypertension

A
Idiopathic
Secondary to left heart disease
Secondary to chronic respiratory diseases 
Chronic theombeoembolic PH
Miscellaneous
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13
Q

Symptoms of pulmonary hypertension

A

Exertional shortness of breath
Chest tightness
Exertional dizziness or light-headedness

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14
Q

Pulmonary hypertension signs

A
Elevated JVP
Right ventricular heave
Loud pulmonary second heart sound
Hepatomegaly - back pressure on venous system and heart
Ankle oedema
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15
Q

Pulmonary hypertension investigations

A
ECG
Lung function tests
Chest x-ray
Echocardiograph
V/Q scan
CT pulmonary angiogram
Right heart catheterisation
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16
Q

Pulmonary hypertension chest x-ray findings

A

Enlarge hila shadows in right lung

17
Q

General treatment of pulmonary hypertension

A

Treat underlying condition
Oxygen
Anticoagulation
Diuretics - increase exertion of fluid

18
Q

Specific treatment of pulmonary hypertension

A

Calcium channel antagonist - amlodipine
Prostacyclin - vasodilator
Endothelin receptor antagonist - bosentan
Riociguat
Phosphodiesterase inhibitors - sildenafil

19
Q

Other treatments of pulmonary hypertension

A

Thromboendarterectomy (CTEPH)

Lung or heart transplant