Pulmonary Vascular Disease Flashcards
Pulmonary embolism
Thrombus forms in the venous system and embolisms to the pulmonary arteries
Major risk factors of PE
Recent major trauma Recent surgery Cancer Significant cardiopulmonary disease Pregnancy Inherited thrombophilia
Symptoms of PE
Pleuritic chest pain Cough Haemoptysis Isolated acute dyspnoea (multiple) Syncope or cardiac arrest (massive)
Signs of PE
Preyxia Pleural rub (walking in snow) Stony dullness to percussion at base (effusion) Tachycardia, tachypnoea, hypoxia Hypotension
PE investigations
FBC, biochemistry troponin 1, blood gases Chest x-ray ECG D-dimer CT pulmonary angiogram V/Q scan Echocardiography
Prognosis of PE based on
Age
Sex
Comorbidity
Physiological parameters
PE treatment
Oxygen Low molecular weight heparin Direct oral anticoagulants - rivaroxaban, apixaban Thrombolysis - alteplase Pulmonary embolectomy Warfarin - anticoagulant
Pulmonary hypertension
Elevated blood pressure in pulmonary arterial tree
Pulmonary hypertension when pulmonary pressure greater than
25mmHg
Idiopathic pulmonary hypertension epidemiology
Young people
Rare
Can be fatal
Secondary pulmonary hypertension epidemiology
Older people
More common
Not usually fatal
Causes of hypertension
Idiopathic Secondary to left heart disease Secondary to chronic respiratory diseases Chronic theombeoembolic PH Miscellaneous
Symptoms of pulmonary hypertension
Exertional shortness of breath
Chest tightness
Exertional dizziness or light-headedness
Pulmonary hypertension signs
Elevated JVP Right ventricular heave Loud pulmonary second heart sound Hepatomegaly - back pressure on venous system and heart Ankle oedema
Pulmonary hypertension investigations
ECG Lung function tests Chest x-ray Echocardiograph V/Q scan CT pulmonary angiogram Right heart catheterisation