Embryology - Development of Respiratory System Flashcards

1
Q

4 main parts of respiratory development

A

Launch a trachea
Construct the lungs
Invest the lungs with pleura
Manufacture a diaphragm

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2
Q

Where does the trachea originate from

A

Ventral walls of foregut (oesophagus)

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3
Q

When does the development of the trachea and lungs begin

A

Week 4

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4
Q

Position of trachea relative to oesophagus

A

Anterior

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5
Q

Name of groove from which tracheal outgrowth begins

A

Laryngotracheal groove

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6
Q

Oesophagotracheal septum

A

Septum that develops between oesophagus and trachea to completely separator them

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7
Q

Fistula

A

Abnormal or surgically made passage between tubular organ and the body surface, or between two hollow or tubular organs

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8
Q

Atresia

A

Condition where an opening or passage in the body is closed or absent

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9
Q

Visceral pleura develops from

A

The splanchnic lateral plate mesoderm

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10
Q

Parietal pleura develops from

A

The somatic lateral plate mesoderm

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11
Q

Name of gap between parietal and visceral pleurae

A

Pleuroperitoneal canal

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12
Q

Pleuroperitoneal folds function

A

Form around primitive heart separating pleural cavities from pericardial cavity

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13
Q

Pleuroperitneal canals develops into

A

Pleural cavity

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14
Q

The lung buds ‘punch’ into

A

The visceral mesoderm

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15
Q

Lung buds expand into the

A

Pericardioperitnoeal canals

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16
Q

Canicular stage

A

Terminal bronchioles give rise to tubes that make up respiratory tract

17
Q

Saccular stage

A

Formation of alveolar sacs

18
Q

Alveolar stage

A

Formation of alveoli from terminal sacs

19
Q

Pseudoglandual stage

A

Setup of all pulmonary structures except elements needed for gas exchange

20
Q

What is the major cause of respiratory distress syndrome (RDS)

A

Surfactant deficiency

21
Q

RDS makes up what percentage of neonatal disease

A

30%

22
Q

Examples of congenital conditions of lungs

A
Accessory lobes
Agenesis of lung
RDS
Lobe of azygos vein
Pulmonary hypoplasia
23
Q

Agenesis of lung

A

Complete non development of a lung

24
Q

Central tendon develops from

A

Septum transversum

25
Q

Primitive diaphragm forms from

A

Pleuroperitoneal membranes

26
Q

Median portion and crura of diaphragm develop from

A

Dorsal mesentery of oesophagus

27
Q

Peripheral parts of diaphragm develop from

A

Muscular ingrowth from lateral body walls

28
Q

Congenital abnormalities of diaphragm

A

Failure of diaphragm to completely close during development

Herniation of abdominal contents into the chest

29
Q

Pulmonary hypoplasia

A

Incomplete development of lungs

30
Q

Diaphragmatic herniae

A

Hernia of diaphragm

31
Q

Hiatal herniae

A

Hernia of stomach through diaphragm opening