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Respiratory System > Non-operative Management of Lung Cancer > Flashcards

Non-operative Management of Lung Cancer Flashcards

1
Q

Percentage of non-small cell carcinomas operable

A

25%

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2
Q

Therapeutic options for lung cancer

A 
Radiotherapy
Surgery 
Chemotherapy
Immunotherapy
Targeted therapies
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3
Q

Essential info to determine optimal therapy

A

Pathology, stage and performance status

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4
Q

Adjuvant therapy

A

Therapy given postoperatively

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5
Q

Adjuvant therapy options in non-small cell carcinoma

A

Chemotherapy

Radiotherapy

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6
Q

Neoadjuvant therapy

A

Therapy given before operating

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7
Q

Stage III non-small cell carcinoma treatment

A

Induction chemotherapy followed by radical radiotherapy

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8
Q

Stereotactic ablative therapy

A

Targeting radiotherapy directly at tumour

Used on tumours up to 4cm and >2cm from airways

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9
Q

Stage IV non-small cell carcinoma treatment

A

Radiotherapy to primary tumour

Chemotherapy

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10
Q

Average chemotherapy cycles in the UK

A

4

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11
Q

Immunotherapy is used for

A

Metastatic disease

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12
Q

Presenting symptom of non-small cell carcinoma bone pain from metastases

A

Pathological fracture

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13
Q

Treatment for non-small cell carcinoma bone pain from metastases

A

Palliative radiotherapy

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14
Q

Non-small cell lung cancer non-operative management

A 
Adjuvant therapy 
Neoadjuvant therapy
Immunotherapy
Radical radiotherapy
Chemotherapy & radiotherapy 
SABR
Targeted drugs
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15
Q

Adjuvant immunotherapy option in non-small cell carcinoma

A

Durvalumab after chemo and RT

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16
Q

Immunotherapy option in non-small cell carcinoma

A

Checkpoint inhibitors

17
Q

Small cell lung cancer limited disease non-operative management

A

Chemotherapy
Immunotherapy
Thoracic and prophylactic cranial radiotherapy

18
Q

Immunotherapy in small cell carcinoma

A

Combination of drugs e.g cisplatin and etoposide

19
Q

Response rate in limited disease small cell carcinoma therapy

A

90%

20
Q

Small cell lung cancer extensive disease non-operative management

A

Chemotherapy
Thoracic and prophylactic cranial radiation
Immunotherapy

21
Q

Immunotherapy for small cell carcinoma brain metastases

A

Steroids

22
Q

Response rate in extensive disease small cell carcinoma therapy

A

80%

23
Q

Side effects of chemotherapy

A 
Marrow suppression 
Nausea and vomiting
Fatigue and lethargy
Neuropathy
Hair loss
Increased risk of MI/stroke
24
Q

Side effects of radiotherapy

A 
Lethargy
Risk to surrounding organs
Pneumonitis
Dysphagia
Fibrosis 
Increased risk of MI and second malignancies
25
Q

Side effects of immunotherapy

A

Inflammation

26
Q

Lung cancer screening given to

A

At risk population

Respiratory System (20 decks)

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