Pulmonary Physiology (Exam 3) Flashcards
What are some pathologies that would cause ventilatory pump dysfunction?
Asthma, high spinal cord injury, collapsed lung, increased kyphosis,
What is restrictive lung disease?
Abnormal reduction in pulmonary ventilation, volume of gas/air moving in and out is decreased.
What is compliance?
The measure of distensibility of a material. increases negative pressure inspiratory muscles need to generate to maintain adequate ventilation. Common cause is pneumonia, CF, occupational exposures (silica dust, coal, asbestos, smoke)
What are the 2 types of compliance?
Chest wall compliance, lung compliance
What cause some changes in elasticity of chest wall?
Skeletal muscle, bone, skin, metabolic, neurological innervations of abdominal or respiratory muscles
What causes changes in lung compliance?
Decreased elasticity of the lungs by pathologic and/or changes associated with aging on lung, pleura or pleural space. More inspiratory muscle forces are required to pull the lungs open
What happens to breathing with increased compliance?
increased work during breathing as greater pressures are needed to maintain ventilatory threshold
What are the three different types of lung issues you can have?
Respiratory pump problems, airway clearance problems, gas exchange problems
What can cause an airway clearance problem?
Alteration in character and content of mucus
alteration in cellular wall of conducting airways
alteration in cilia function
alteration in force production/efficacy of cough
How does O2/CO2 diffuse?
Gas diffuses from high pressure to low pressure from the alveoli to capillary
What does the oxyhemoglobin curve describe?
“Hemobglobins affinity for oxygen” or how readily hemoglobin acquires and releases oxygen molecules
What happens to the oxyhemoglobin curve as the PO2 increases?
Curve increases
