Blood Disorder Flashcards
What are the values that correspond with anemia?
♂: Hgb < 13-18 g/100ml
♀: Hgb < 12-16 g/100 ml
What are three causative factors for anemia?
- Excessive blood loss
- Destruction of erythrocytes
- Decreased or faulty erythrocyte production
Autosomal recessive disorder where there is abnormality in hemoglobin is known as ________.
sickle cell disease
Sickle cell presentations include chronic hemolytic anemia, vaso-occlusion, and sickle cell crisis caused by the following physiologic stressors:
Viral or bacterial infection Hypoxia Dehydration Extreme temperatures ETOH Fatigue
Incomplete of abnormal fx of Hgb with presentation of severe anemia that leads to endocrine, cardiac, and liver pathology is called ___________.
Thalessemia
Thalessemia is caused by _________ in the 4 HgB genes.
1-4 abnormalities
Increased RBCs occur with which condition?
Polycthemia Vera
Primary polycthemia vera is excess RBCs due to ___________.
bone marrow abnormality
Secondary polycthemia vera is often caused by prolonged hypoxia (altitude or obstructive lung disorders) which results in increased erthropoietin. What type of disorders are associated?
Renal disorder
The following presentations are consistent with ______ WBC counts, known as ____________.
o Dehydration
o Tachycardia
o Mental status change
low WBC = leukocytosis
The following presentations are consistent with ________.
o Increased infection risk with low WBC (neutropenia)
o Increased precautions that are facility dependent
leukopenia
myelo- leukemias involve:
bone marrow
lympho- leukemias involves
lymphatic system
Which major leukemia type is responsive to chemo?
acute (50% cured with chemo!)
Which major leukemia type is NOT responsive to chemo?
chronic
Decreased # of platelets is known as
thrombocytopenia
Increased # of platelets is known as
throbocytosis OR throbocythemia
Platelet dysfxn can be congenital or caused by ______.
drugs
Usually no manual muscle testing with ________ cells/mm3 due to increased risk of _________.
< 50,000 cells/mm3
increased risk of bleeding!
Abnormal plasma clotting protein is known as
hemophilia
Which factors are typically deficient with hemophilia?
factor VIII or IX deficiency
What is hemarthrosis?
bleeding into jts with subsequent contractures
When platelet count is > 50,000 cells/mm^3, activity level is
unrestricted
When platelet count is < 5,000-10,000 cells/mm^3, activity level is
bedrest
When platelet count is 30,000-50,000 cells/mm^3, activity level is
AROM and moderate exercise
When platelet count is 10,000-20,000 cells/mm^3, activity level is
ADLs
When platelet count is 20,000-30,000 cells/mm^3, activity level is
AROM and light exercise