Püd Flashcards

1
Q
  1. What is the most proximal abdominal organ of the digestive tract?
A

The stomach.

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2
Q
  1. What are the gross anatomic parts of the stomach?
A

Fundus

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3
Q
  1. What are the main arterial supplies to the stomach?
A

Left gastric artery

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4
Q
  1. What are the main venous drainages of the stomach?
A

Left gastric vein

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5
Q
  1. What is the role of the vagus nerve in stomach innervation?
A

It affects secretion

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6
Q
  1. What are the four layers of the gastric wall?
A

Mucosa

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7
Q
  1. What are the main functions of the stomach?
A

Stores food

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8
Q
  1. What is peptic ulcer disease (PUD)?
A

Focal defects in the gastric or duodenal mucosa that extend into the submucosa or deeper.

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9
Q
  1. What causes peptic ulcers?
A

An imbalance between mucosal defenses and acid/peptic injury.

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10
Q
  1. What are the main etiologies of peptic ulcer disease?
A

H. pylori infection

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11
Q
  1. What is the final common pathway to ulcer formation?
A

Acid-peptic injury of the gastroduodenal mucosal barrier.

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12
Q
  1. What percentage of peptic ulcers are duodenal ulcers?
A

Two-thirds of all peptic ulcers.

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13
Q
  1. Where are most duodenal ulcers located?
A

Within the first portion of the duodenum.

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14
Q
  1. What is the typical size of duodenal ulcers?
A

Most are less than 1 cm in diameter.

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15
Q
  1. What is the gender prevalence of duodenal ulcers?
A

Twice as common in men compared to women.

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16
Q
  1. What is the relationship between gastric ulcers and cancer?
A

Gastric ulcers are strongly related to cancer

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17
Q
  1. What is the typical pain pattern for gastric ulcers?
A

Pain more commonly occurs with eating.

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18
Q
  1. What is the most common type of gastric ulcer?
A

Johnson type I

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19
Q
  1. What is the acid secretion pattern in Johnson type I gastric ulcers?
A

Normal or decreased acid secretion.

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20
Q
  1. What is Johnson type II gastric ulcer associated with?
A

Active or quiescent duodenal ulcer disease and excess acid secretion.

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21
Q
  1. What is Johnson type III gastric ulcer?
A

Prepyloric ulcers

22
Q
  1. Where do Johnson type IV gastric ulcers occur?
A

Near the gastroesophageal (GE) junction.

23
Q
  1. What is the acid secretion pattern in Johnson type IV gastric ulcers?
A

Normal or below normal.

24
Q
  1. What are Johnson type V gastric ulcers associated with?
A

Long-term NSAID use.

25
Q
  1. What are the common clinical manifestations of peptic ulcer disease?
A

Abdominal pain (burning

26
Q
  1. What are the common complications of peptic ulcer disease?
27
Q
  1. What is the most common complication of peptic ulcer disease?
A

Bleeding peptic ulcer.

28
Q
  1. What are the typical presentations of a bleeding peptic ulcer?
29
Q
  1. What is the first step in managing a bleeding peptic ulcer?
A

Secure IV line and resuscitate the patient.

30
Q
  1. What is the role of endoscopy in managing bleeding peptic ulcers?
A

Injection with epinephrine

31
Q
  1. What is the typical presentation of a perforated peptic ulcer?
A

Acute abdomen with severe

32
Q
  1. What are the stages of perforation in peptic ulcer disease?
A

Stage of chemical peritonitis

33
Q
  1. What diagnostic tests are used for perforated peptic ulcers?
34
Q
  1. What is the treatment for perforated peptic ulcers?
A

Secure IV line

35
Q
  1. What percentage of patients with PUD develop gastric outlet obstruction?
36
Q
  1. What are the typical symptoms of gastric outlet obstruction?
37
Q
  1. What is the treatment for gastric outlet obstruction?
A

Nasogastric suction

38
Q
  1. What is intractable or nonhealing peptic ulcer?
A

A peptic ulcer that does not heal despite standard treatment.

39
Q
  1. What is the role of H. pylori in peptic ulcer disease?
A

H. pylori is responsible for the majority of cases of PUD.

40
Q
  1. What is the role of NSAIDs in peptic ulcer disease?
A

NSAIDs are a major risk factor for PUD due to their effect on mucosal defenses.

41
Q
  1. What is Zollinger-Ellison syndrome (ZES)?
A

A condition caused by gastrinoma leading to excessive acid secretion and peptic ulcers.

42
Q
  1. What is the role of serum gastrin testing in PUD?
A

To diagnose Zollinger-Ellison syndrome or other conditions causing hypergastrinemia.

43
Q
  1. What is the role of endoscopy in diagnosing PUD?
A

Endoscopy is the gold standard for visualizing ulcers and obtaining biopsies.

44
Q
  1. What is the role of H. pylori testing in PUD?
A

To confirm H. pylori infection

45
Q
  1. What is the role of PPI (proton pump inhibitors) in PUD treatment?
A

PPIs reduce acid secretion

46
Q
  1. What is the role of angiography in managing bleeding PUD?
A

Angiography can be used for embolization to stop bleeding in cases where endoscopy fails.

47
Q
  1. What is the role of surgery in PUD?
A

Surgery is used for complications like perforation

48
Q
  1. What is the typical acid secretion pattern in duodenal ulcers?
A

Increased acid secretion.

49
Q
  1. What is the typical acid secretion pattern in gastric ulcers?
A

Variable acid secretion

50
Q
  1. What is the role of histology in diagnosing PUD?
A

Histology helps differentiate between benign ulcers and malignant lesions