Benign Diseas Of Liver Flashcards
- What are the most common benign liver tumors?
Hemangioma
- What percentage of the population has benign liver lesions?
Up to 20%.
- What is the most common benign liver tumor?
Hepatic hemangioma.
- What is the gender predominance for hepatic hemangiomas?
60-80% occur in females.
- What is the typical age of presentation for hepatic hemangiomas?
Third to fifth decades of life.
- What is the proposed role of estrogen in hepatic hemangiomas?
Estrogens may play a role in their pathogenesis
- What is the blood supply of hepatic hemangiomas?
Derived from the hepatic artery.
- What is considered a giant hemangioma?
Hemangiomas larger than 5 cm.
- What are the microscopic features of hepatic hemangiomas?
Benign endothelium along vascular channels separated by thin connective tissue.
- What are the clinical features of hepatic hemangiomas?
Typically asymptomatic
- What are the life-threatening complications of hepatic hemangiomas?
Rupture
- What is the mortality rate for spontaneous rupture of a hepatic hemangioma?
Approximately 35%.
- What imaging findings are diagnostic for hepatic hemangiomas on CT?
Early peripheral nodular enhancement with centripetal filling.
- What is the sensitivity and specificity of MRI for hepatic hemangiomas?
91% sensitivity and 92% specificity.
- What is the treatment for asymptomatic hepatic hemangiomas?
Observation with no follow-up imaging for lesions ≤5 cm.
- What are the indications for surgical intervention in hepatic hemangiomas?
Severe symptoms
- What is focal nodular hyperplasia (FNH)?
The second most common benign solid liver tumor
- What is the gender predominance for FNH?
8:1 female-to-male ratio.
- What is the typical age of presentation for FNH?
35 years old.
- What is the association between FNH and oral contraceptives?
Controversial
- What are the pathological features of FNH?
Central scar (80%) and bile duct proliferation (100%).
- What is the treatment for FNH?
Observation
- What is hepatocellular adenoma?
A benign liver tumor predominantly seen in young females
- What is the gender predominance for hepatocellular adenoma?
11:1 female-to-male ratio.
- What are the risk factors for hepatocellular adenoma?
OCP use