Benign Diseas Of Liver Flashcards

1
Q
  1. What are the most common benign liver tumors?
A

Hemangioma

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2
Q
  1. What percentage of the population has benign liver lesions?
A

Up to 20%.

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3
Q
  1. What is the most common benign liver tumor?
A

Hepatic hemangioma.

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4
Q
  1. What is the gender predominance for hepatic hemangiomas?
A

60-80% occur in females.

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5
Q
  1. What is the typical age of presentation for hepatic hemangiomas?
A

Third to fifth decades of life.

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6
Q
  1. What is the proposed role of estrogen in hepatic hemangiomas?
A

Estrogens may play a role in their pathogenesis

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7
Q
  1. What is the blood supply of hepatic hemangiomas?
A

Derived from the hepatic artery.

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8
Q
  1. What is considered a giant hemangioma?
A

Hemangiomas larger than 5 cm.

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9
Q
  1. What are the microscopic features of hepatic hemangiomas?
A

Benign endothelium along vascular channels separated by thin connective tissue.

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10
Q
  1. What are the clinical features of hepatic hemangiomas?
A

Typically asymptomatic

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11
Q
  1. What are the life-threatening complications of hepatic hemangiomas?
A

Rupture

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12
Q
  1. What is the mortality rate for spontaneous rupture of a hepatic hemangioma?
A

Approximately 35%.

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13
Q
  1. What imaging findings are diagnostic for hepatic hemangiomas on CT?
A

Early peripheral nodular enhancement with centripetal filling.

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14
Q
  1. What is the sensitivity and specificity of MRI for hepatic hemangiomas?
A

91% sensitivity and 92% specificity.

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15
Q
  1. What is the treatment for asymptomatic hepatic hemangiomas?
A

Observation with no follow-up imaging for lesions ≤5 cm.

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16
Q
  1. What are the indications for surgical intervention in hepatic hemangiomas?
A

Severe symptoms

17
Q
  1. What is focal nodular hyperplasia (FNH)?
A

The second most common benign solid liver tumor

18
Q
  1. What is the gender predominance for FNH?
A

8:1 female-to-male ratio.

19
Q
  1. What is the typical age of presentation for FNH?
A

35 years old.

20
Q
  1. What is the association between FNH and oral contraceptives?
A

Controversial

21
Q
  1. What are the pathological features of FNH?
A

Central scar (80%) and bile duct proliferation (100%).

22
Q
  1. What is the treatment for FNH?
A

Observation

23
Q
  1. What is hepatocellular adenoma?
A

A benign liver tumor predominantly seen in young females

24
Q
  1. What is the gender predominance for hepatocellular adenoma?
A

11:1 female-to-male ratio.

25
Q
  1. What are the risk factors for hepatocellular adenoma?