Psychiatry Flashcards
What are 2 lesser known drugs (a-2 agonists) for ADHD?
- Clonidine
2. Guanfacine
What dx presents with increased sleep, weight, and appetitie, with interpersonal rejection sensitivity and extremities feeling heavy?
Major depression with atypical features
With MAOIs, what will foods rich in tyramine cause?
HTN
What type of drugs are phenelzine, isocarboxazid, and tranylcypromine?
MAOIs
What dx presents with agitation, confusion, sweating, hyperthermia, nausea, diarrhea, tremors, myoclonus?
Serotonin syndrome
What’s the tx for serotonin syndrome?
Cyproheptadine
How long must the sx of schizophrenia be present for the diagnosis?
6 mos
What’s the first line tx for schizophrenia?
Atypical antipsychotic
When do you use clozapine?
If patients do not respond to 2 adequate trials of other antipsychotics
Which antipsychotic has a greater incidence of diabetes and weight gain?
Olanzapine
Which antipsychotic has a greater incidence of movement disorders?
Risperidone
Which antipsychotic has a lower incidence of movement disorders?
Quietiapine
Which antipsychotic has an increased risk of QT prolongation, avoid in patients with conduction defects?
Ziprasidone
Which antipsychotic has a high risk of agranulocytosis and cardiomyopathy?
Clozapine
Which antipsychotic has a higher risk of compulsive behavior like gambling?
Aripiprazole
Which antipsychotic is safer to use in pregnant patients?
Lurasidone
What are the side effects of the “pines?”
Weight gain, metabolic syndrome, diabetes
What are the side effects of the “dones?”
Movement disorders, cardiac conduction problems
Which 2 antipsychotics have the least likelihood of causing weight gain and diabetes?
Aripriprazole and ziprasidone
“Fix the rip in the zipper because you’re not gaining weight”
What are 3 drugs to treat acute dystonia?
- Benztropine
- Trihexylphenidyl
- Diphenhydramine
What’s the tx for akathisia?
B-blockers, benzos, switch to atypical or reduce drug
What’s the tx for tardive dyskinesia?
Valbenazine; switch to atypical; clozapine has least risk
Which 2 intoxications present with euphoria, hypervigilance, autonomic hyperactivity, pupillary dilation, and perceptual disturbances?
- Amphetamine
2. Cocaine
Which intoxication presents with perceptual disturbances, impaired judgement, tremor, and dissociation?
Hallucinogens
