Pediatrics Flashcards
Do you suction the nose first or do the cord ABG?
Suction
How many weeks defines a term neonate?
38
How many weeks defines late preterm?
34-37
What’s a normal RR in a neonate?
40-60 breaths/min
What’s a normal HR in a neonate?
120-160 beats per minute
T/F: a low score on the Apgar is not associated with future cerebral palsy?
True
What are the 5 criteria of the apgar scoring?
- Appearance
- Pulse
- Grimace
- Activity
- Respiration
What’s the most likely cause of conjunctivitis at 1 day after birth?
Chemical irritation
What’s the most likely cause of conjunctivitis at 2-7 days after birth?
Neisseria gonorrhoeae
What’s the most likely cause of conjunctivitis at 7+ days after birth?
Chlamydia trachomatis
What’s the most likely cause of conjunctivitis at 3+ weeks?
Herpes
What’s the mnemonic to remember the causes of newborn conjunctivitis by time after birth?
My chemical romance is gone with the track, herpes
What’s a cause of intracranial bleeding 1 week after birth?
Vit K deficiency (if didn’t receive the shot at birth)
What’s the most common intraocular malignancy of childhood?
Retinoblastoma
Is Rb a tumor suppressor?
Yes
Which chromosome is Rb on?
Chromosome 13
How does retinoblastoma present?
White reflex in a child under age 3
What will show up on dilated opthalmologic exam in retinoblastoma?
White retinal mass with friable consistency
Do you biopsy retinoblastoma?
No, there is risk of seeding
How do anesthetics affect the neonate?
Respiratory and CNS depression
How do barbiturates affect the neonate?
Respiratory and CNS depression, dilated pupils
How does magnesium sulfate affect the neonate?
Respiratory depression
How do sulfonamides affect the neonate?
Displaces bilirubin from albumin
How do NSAIDs affect the neonate?
Premature closure of the PDA
How does warfarin affect the neonate?
Facial dysmorphism and chondrodysplasia
How does isotretinoin affect the neonate?
Facial and ear anomalies, congenital heart disease
How does phenytoin affect the neonate?
Hypoplastic nails, IUGR
How does DES affect the neonate?
Clear-cell adenocarcinoma of the vagina or cervix
How does tetracycline affect the neonate?
Enamel hypoplasia, discolored teeth
How does valproate/carbamazapine affect the neonate?
Intellectual disability, neural tube defects
How do ACE inhibitors affect the neonate?
Craniofacial abnormalities
What bacteria normally helps make vitamin K and clotting factors?
E coli
What’s the inheritance pattern of G6PD deficiency?
XLR
What’s the inheritance pattern of PKU?
AR
What’s the treatment of PKU?
Special diet low in phenylalanine
What’s the treatment of galactosemia?
Cutting out all lactose-containing products
What’s the inheritance pattern of CAH?
AR
What are the 3 main infectious contraindications to breastfeeding?
- HIV
- TB
- Herpes of the nipple
Is splenomegaly a normal finding in newbors?
Yes
What dx presents with tachypnea within a couple hours of delivery, resolves within 1-5 days?
TTN
What dx presents with tachypnea in preterm infants?
RDS
If tachypnea in a newborn lasts more than 4 hours, what should be tested?
Blood and urine cultures
Is an egg allergy a contraindication to MMR, yellow fever, or influenza vaccine?
No
Is a reaction to a previous DPT with fever, or a FH of seizures or SIDS contraindication to vaccinations?
No
What’s the diff between caput succedaneum and cephalohematoma?
Caput is not caput (it crosses suture lines)
Which spinal cord level is Erb palsy?
C5-C6
Which spinal cord level is claw hand?
C7-C8 +/- T1
Can claw hand also have Horner’s syndrome?
Yes
What are the 2 causes of polyhydramnios?
- Werdnig-Hoffman
2. Intestinal atresia
What are the 2 main causes of oligohydramnios?
- Renal agenesis/Potter sequence
2. Prune belly (lack of abdominal muscles)
What neonatal syndrome causes airway obstruction and appears as patchy infiltrates and flattening of diaphragm on CXR?
Meconium aspiration syndrome
Which neonatal dx occurs in premies and presents with abdominal distension, bilious vomiting, rectal bleeding, and diarrhea, with crepitus?
Necrotizing enterocolitis
What’s the tx for necrotizing enterocolitis?
NG tube, broad spectrum abx, surgery if needed
T/F: diaphragmatic hernia can cause respiratory distress in premies?
True, it’s different from a hiatal hernia in adults
What dx is a defect in which intestines and organs form beyond the abdominal wall with a sac covering?
Omphalocele
What syndrome is omphalocele associated with?
Edwards (trisomy 18)
What 2 things does elevated AFP mean?
- Neural tube defects
2. Abdominal wall defects
T/F: 90% of umbilical hernias close by age 3?
True; if not, surgery is needed
What dx is a wall defect lateral to midline with intestines and organs forming beyond the abdominal wall but without any sac covering?
Gastroschisis
“Gasp that’s bad”
What dx is a large, palpable abdominal mass due to hemihypertrophy of one kidney?
Wilms tumor
What’s the most common abdominal mass in children?
Wilms tumor
What’s the best initial study for Wilms tumor?
US
What’s the tx for Wilms tumor?
Total nephrectomy with chemo and radiation
What dx is an adrenal medulla tumor similar to pheochromocytoma but with fewer cardiac presentations, with increased vanillyl mandelic acid and metanephrines on urine?
Neuroblastoma
What congenital dx is characterized by overriding aorta, pulmonary stenosis, RVH, and VSD?
Tetralogy of Fallot
What murmur is present in Tetralogy of Fallot?
Holosystolic murmur at LLS border
What does a CXR show in Tetralogy?
Boot shaped heart
How does squatting help in Tetralogy?
Increased preload and increased SVR (decreased R to L sunt and decreased pulmonary resistance)
Which 3 trisomies commonly have VSD?
- Trisomy 21
- Trisomy 13
- Trisomy 18
There are only 3 holosystolic murmurs:
- Mitral regurgitation
- Tricuspid regurgitation
- VSD
What dx presents with early, severe cyanosis, single S2, and egg on a string on CXR?
Transposition of the Great Vessels
How do you treat Transposition of the Great Vessels?
PG E1 to keep ductus open and 2 surgeries
What’s the prognosis for Transposition of the Great Vessels?
Poor, only 1 in 4 will survive the surgeries
What does pulsus alternans signify?
LV systolic dysfunction
Which dx presents with gray cyanosis (rather than blue), single S2, hyperdynamic precordium, and a globular shaped heart with pulmonary edema?
Hypoplastic L Heart Syndrome
What’s the tx for Hypoplastic L Heart Syndrome?
3 surgeries or a heart transplant
What dx occurs when a single trunk emerges from both L and R ventricles and gives rise to all major circulations?
Truncus arteriosus
What dx presents with severe dyspnea after birth and early and frequent respiratory infex, as well as single S2 and a systolic ejection murmur?
Truncus arteriosus
What’s the tx for truncus arteriosus?
Surgery
What will happen if surgery is not performed in truncus arteriosus?
Pulmonary HTN
What dx causes no venous return between pulmonary veins and the L atrium, and oxygenated blood instead returns to the SVC, dx with echocardiogram and tx with surgery?
Total anomalous pulmonary venous return
What dx presents with severe cyanosis in a newborn with CXR showing decreased pulmonary flow and EKG showing L axis deviation?
Tricuspid valve atresia
What’s the tx for tricuspid valve atresia?
PG E1, surgical aortopulmonary shunt
What type of hypertrophy occurs due to VSD?
RV hypertrophy
Is pansystolic the same as holocystolic?
Yes
Do VSD’s usually close?
Yes within 1-2 years
If it doesn’t close, do VSD’s need surgery?
Yes
What defect can clots pass through in the heart and cause stroke?
ASD
Do ASD’s need to be fixed?
Yes if symptomatic but most close on their own
How do you close a PDA?
Indomethacin
What does a pear shaped heart on CXR indicate?
Pericardial effusion
What does a boot-shaped heart on CXR indicate?
Tetralogy of Fallot
“Tetra is a boot maker”
What does a jug handle appearance on CXR indicate?
Primary pulmonary artery HTN
“Bring a jug of PAH to the lab?
What does a “3”-like appearance or rib notching on CXR indicate?
Coarctation of the aorta
‘3 Coarctee”
What genetic condition often includes a coarctation of the aorta?
Turner’s syndrome
What syndrome presents with cardiac problems and hearing loss?
Congenital long QT syndrome
What’s the best medication for long QT syndrome?
B-blocker
What condition presents with some of the following: migratory polyarthritis, carditis, erythema marginatum, chorea, fever, elevated ESR?
Rheumatic fever
What congenital heart defect has a downwardly displaced tricuspid valve into the R ventricle and is associated with maternal lithium use?
Ebstein anomaly