Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

First Aid > Psych Pharm > Flashcards

Psych Pharm Flashcards

1
Q

Drugs for ADHD

A

Methylphenidate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Drugs for Alcohol withdrawal

A

benzos

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Drugs for anxiety

A

SSRIs, SNRIs, buspirone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Drugs for bipolar

A

mood stabilizers: lithium, valproic acid, carbamazepine

atypical antipsychotics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Drugs for bulimia

A

SSRIs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Drugs for depression

A

SSRIs, SNRIs, TCAs, buproprion, mirtazapine (esp with insomnia)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Drugs for OCD

A

SSRIs, clomipramine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Drugs for panic d/o

A

SSRIs, venlafaxine, benzodiazepines

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Drugs for PTSD

A

SSRIs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Drugs for schizophrenia

A

antipsychotics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Drugs for social phobias

A

SSRIs, beta-blockers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

drugs for tourette syndrome

A

antipsychotics (haloperidol, risperidone)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

CNS stimulants

A

methyl phenidate, desctroamphetamine, methamphetamine, phentermine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

CNS stimulant MOA

A

inc. catecholamines (NE and DA esp) at synaptic cleft

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

CNS stimulant use

A

ADHD, narcolepsy, appetite control

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Antipsychotics/ neuroleptics

A

haloperidol, trifluoperazine, fluphenazine, thioridazine, chlorpromazine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Antipsychotic MOA

A

block D2 receptors and increase cAMP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

which anti psychotics have high potency

A

trifluoperazine, fluphenazine, haloperidol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

which antipsychotics have low potency

A

chlorpromazine, thiridazine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

what side effects do you experience with high potency antipsychotics?

A

neurological (extrapyramidal SEs)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

SE of low potency anti-psychotics

A

anticholinergic, antihistamine and a1 blockade effects

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

SE of chlorpromazine

A

corneal deposits

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

SE of thioridazine

A

retinal deposits

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

SE of haloperidol

A

NMS and tardive dyskinesia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

clinical uses of antipsychotics

A

schizophrenia, psychosis, acute mania, tourettes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

antipsychotics: lipid or water soluble?

A

highly lipid soluble

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

extrapyramidal side effects of antipsychotics? Treatment?

A

dyskinesia

benstropine or diphenhydramine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

Endocrine SE of antipsychotics

A

DA antagonism leads to hyperprolactinemia and galactorrhea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

SE of antipsychotics?

A

EPS - dyskinesia
endocrine - DA antag –> hyperprolactinemia, galactorrhea
muscarinic block –> dry mouth, constipation
a1 block –> hypotension
histamine block –> sedation
NMS
tardive dyskinesia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

What is the evolution of EPS SE?

A

4hr: acute dystonia
4 day: akathisia (restless)
4 week: bradykinesia
4 month: tardive dyskinesa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

What is neuroleptic malignant syndrome?

A

Fever, Encephalopathy, Vitals unstable, Enzymes increase, Rigidity of muscles

32
Q

How do you treat NMS

A

dantroline, D2 agonists (bromocriptine)

33
Q

what is tardive dyskinesia?

A

oral facial movements from long term antipsychotic use

34
Q

What are the atypical antipsychotics?

A

olanzapine, clozapine, quetiapine, risperidone, aripiprazole

35
Q

MOA of atypical antipsychotics?

A

unknown, varied 5HT2, DA, alpha and H1 R effects

36
Q

what are the clinical uses of atypical antipsychotics?

A

schizophrenia, bipolar, OCD, anxiety, depression, mania, tourettes

37
Q

what are the SE of olanzapine

A

weight gain

38
Q

what are the SE of clozapine

A

weight gain

agranulocytosis

39
Q

what are the SE of risperidone

A

increased prolactin causing decreased GnRH, LH and FSH

40
Q

what are the SE of ziprasidone

A

prolonged QT

41
Q

MOA of lithium

A

not established, maybe IP3 cascade

42
Q

clinical use of lithium

A

mood stabilizer for bipolar, blocks relapse and acute manic events, SIADH

43
Q

SE of lithium

A

tremor,sedation, edema, heart block, hypothyroid, polyuria, teratogenic

44
Q

How is lithium excreted

A

renally and reabsorved at PCT

45
Q

MOA of buspirone

A

stimulates 5HT1A

46
Q

clinical uses of buspirone

A

GAD (need 1 to 2 weeks), not sedative, addictive. Can take with EtOH

47
Q

What are the SSRIs?

A

fluoxetine, paroxetine, sertraline, citalopram

48
Q

MOA of SSRIs

A

5HT specific reuptake inhibitors

49
Q

clinical uses of SSRIs

A

depression, GAD, Panic d/o, OCD, bulimia, social phobias, PTSD. Takes 4 - 8 weeks

50
Q

what are the SE of SSRIs?

A

GI distress, sexual dysfunction.

51
Q

what is serotonin syndrome?

A

increased 5HT can lead to hyperthermia, confusion, myoclonus, cardiovascular collapse, dlushing, diarrhea and seizures

52
Q

how do you treat serotonin syndrome?

A

cyproheptadine which is a 5HT2 receptor antagonist

53
Q

what are the SNRIs

A

venlafaxine, duloxetine

54
Q

MOA of SNRIs

A

5HT and NE reuptake inhibitors

55
Q

clinical use of SNRIs

A

depression, GAD, panic d/o, duloxetine also for diabetic peripheral neuropathy

56
Q

what are the SE of SNRIs

A

increased BP, stimulant effects, sedation, nausea

57
Q

what are the TCAs?

A

amitriptyline, nortriptyline, imipramine, desipramine, clomipramine, doxepin, amoxapine

58
Q

MOA of TCAs

A

block reuptake of NE and 5HT

59
Q

clinical uses of TCAs

A

major depression, OCD (clomipramine), fibromyalgia

60
Q

what are the SE of TCAs?

A

sedation
a1 blocking (postural hypoTN
atropine like effects (tachycardia, urinary retention, dry mouth)
convulsions, coma, cardiotoxicity, respiratory depression, hyperpyrexia, confusion

61
Q

which TCA has more anticholinergic effects?

A

amitriptyline in comparison to nortriptyline

62
Q

what are the SE of desipramine?

A

less sedating than other TCAs but higher seizure incidence

63
Q

MAO inhibitors

A

tranylcypromine, phenelzine, isocarboxazid, selegiline

64
Q

MOA of MAO inhibitors

A

increase NE, 5HT, and DA

65
Q

clinical uses of MAO inhibitors

A

atypical depression, anxiety, hypochondriasis

66
Q

SE of MAO inhibitors

A 
hypertensive crisis (ingestion of tyramine: wine and cheese)
CNS stimulation
67
Q

With what drugs are MAO inhibitors contraindicated and why?

A

SSRIs, TCAs, St. John’s wort., meperidine, and dextromethorphan b/c of serotonin syndrome

68
Q

clinical use of buproprion

A

smoking cessation

69
Q

MOA of buproprion

A

unknown, but increase NE and DA

70
Q

SE of buproprion

A

stimulant: tachycardia, insomnia
headache
seizure in bulimics

71
Q

MOA of mirtazapine

A

a2 antagonist –> increase release of NE and 5HT

potent 5HT2 and 5HT3 receptor antagonist

72
Q

SE of mirtazapine

A

sedation, increased appetite, weight gain, dry mouth

73
Q

what are the atypical antidepressants?

A

bupropiion, mirtazapine, trazodone

74
Q

MOA of trazadone

A

block 5HT2 and a1 receptors

75
Q

clinical uses of trazadone

A

insomnia, high dose needed for antidepressent effects

76
Q

SE of trazadone

A

sedation, nausea, priapism, postural hypotension

First Aid (23 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions