Psoriasis Flashcards
What is a T cell mediated AI disease?
psoriasis
What causes this?
overactive immune system, increased C reactive protein
What are some triggers?
skin injury, infections, HIV, hypocalcemia, pregnancy, stress, drugs, ETOH, smoking, obesity
sharply demarcated erythematous plaques with thick white scale (elbows, knees, trunk, parasacrum, scalp); usually symmetrical but doesn’t have to be; may be itchy during flare
classic psoriasis vulgaris
What is erythrodermic psoriasis?
MEDICAL EMERGENCY if pt feels ill - 90% body
shiny erythematous plaques that have no scale because of constant friction in involved areas (axillae, inframammory folds, and groin); can be extremely itchy
Inverse psoriasis
dew drop shaped papules and plaques (trunk, extremities); most common in children, esp post-strep infection; usually self-limited but can be a sign that child will develop psoriasis in future (guttate means “droplike”)
guttate psoriasis
filtration of inflammatory neutrophils cause sterile pustules (generalized or localized); triggers include pregnancy, tapering of steroids, certain biologics, hypocalcemia, infections, irritants; debilitating
pustular psoriasis
sterile pustules with brown macules and sometimes peeling; most pts have psoriasis only in these locations; hardest to treat; usually caused by smoking, infections and stress
pustulosis of palms and soles
large, well-defined and localized plaques with thick white scale, extremely itchy, can be mistaken for seb derm but will extend onto forehead
Scalp psoriasis
How do you differentiate scalp psoriasis from seborrheic dermatosis?
scalp goes onto forehead