Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Dermatology - Clinical Medicine IV > Drug Eruptions > Flashcards

Drug Eruptions Flashcards

You may prefer our related Brainscape-certified flashcards:
Dermatology Board Prep flashcards
1
Q

What is ACDR?

A

adverse cutaneous drug reactions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is ACDR most common at?

A

skin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is the etiology of ACDR?

A

immunologic, nonimmunologic, idiosyncratic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Who is at high risk of ACDR?

A

women, elderly, immunocompromised, number of drugs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are common drugs that you can have reaction to?

A 
Penicillins
Aminopenicillins
Sulfonamides
Cephalosporins
Packed RBCs
NSAIDS
Tetracyclines
Fluoroquinolones
Anticonvulsants
Allopurinol
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is the most common drug reaction?

A

exanthematous drug reactions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

When do you get a EDR?

A

4-14 days after starting meds

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What can cause EDR?

A

any drug, pcn, carbamazepine, allopurinol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Does EDR have systemic involvement?

A

its low

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is the clinical presenation of EDR?

A 
pruritis, low grade fever
erythematous macules/papules = confluent, sheet like
symmetrical trunk and extremities
no mucosal involvement
worse before it gets better
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is the treatment for EDR?

A

supportive, oral antihistamines, steroids (Oral vs IV vs Topical)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is AGEP?

A

acute generalized exanthematous pustulosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

How many cases of AGEP are there a year?

A

1-5 cases/million

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

When is the onset of AGEP?

A

1-3 weeks after drug administration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is AGEP associated with?

A

fever, leukocytosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

How does AGEP present?

A

diffuse, edematous erythema starts in folds and face

17
Q

How does fixed drug reaction present?

A

solitary erythematous patch or plaque +/- pruritic painful burning

18
Q

When is the onset of fixed drug reactions?

A

30 min 8 hrs after drug ingestation

19
Q

How do you treat fixed drug reaction?

A

stop the drug, +/- steroids, ABX

20
Q

What is DRESS?

A

drug reaction with eosinophilia and systemic syndrome

21
Q

What is the clinical presentation of DRESS?

A

fever, malaise, facial edema, affects liver, heart, lungs, joints, muscules

22
Q

What is the onset of DRESS?

A

2-6 wks after drug ingestion

antielipetics and sulfonamides

23
Q

What do the lesions look like in DRESS?

A

morbiliform eruption to exfoliative dermatitis

face, upper trunk, extremities

24
Q

What is the treatment of DRESS?

A

glucocorticoids

25
Q

When does warfarin induced cutaneous necorsis occur?

A

3-5 days after initiation

26
Q

What are the lesions like in warfarin necrosis?

A

petechiae to ecchymosis to hemoorrhagic infarcts to necrosis

areas high in subq fat

27
Q

What are common medications for warfarin necrosis?

A

heparin, interferon alpha

Dermatology - Clinical Medicine IV (31 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions