Angioedema Flashcards

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1
Q

Swelling into dermis and subcutaneous tissue

A

angioedema

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2
Q

What does angioedema involve?

A

Eyelids, lips, tongue and extremities
Respiratory system
GI system

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3
Q

What causes angioedema?

A
Idiopathic
Hypersensitivity (food, drugs, insect stings)
Physical stimuli (cold, pressure, exercise)
Autoimmune disease
Infection
Ace inhibitors
NSAIds
Hereditary- deficiency of c1-INH
Acquired- result of other diseases
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4
Q

Who get angioedema more?

A

female, no race predilection, all ages

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5
Q

What hx do you want for angioedema?

A
FH of angioedema
New food or medications
Potential triggers/exacerbating factors
Medical conditions
History of urticaria
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6
Q

What do you do on physical exam?

A

airway assessment, inspection, look for GI involvement - presentation varies

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7
Q

What is the work up for angioedema?

A
Similar to urticaria
Identifying the trigger
C4 levels for evaluate for acquired and hereditary
Imaging
Not routinely performed
? Abdominal CT
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8
Q

What is the treatment for angioedema?

A
Life-threatening- Epinephrine 
Antihistamines
\+/- glucocorticoids
Hereditary Angioedema
C1-INH replacement therapy
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