Basal Cell Carcinoma

Question 1

What does the biopsy look like on BCC?

Answer 1

nest of basaloid cells, peripheral palisading, fibromyxoid stroma, cleft formation

Question 2

What is the first step in BCC dx?

Answer 2

first do biopsy then if known surgical removal

Question 3

What is the most common skin cancer?

Answer 3

BCC

Question 4

Where does BCC arise from?

Answer 4

basal layer

Question 5

What is the etiology of BCC?

Answer 5

UV radiation induces DNA damage

PTCH (tumor suppressor gene) mutation

Question 6

What are the risk factors for BCC?

Answer 6

skin type I and II, severe actinic sun damage, male gender, over 60 yo, immune suppression, genetic condition

Question 7

What is the most common subtype of BCC?

Answer 7

nodular

Question 8

Pearly papule or nodule with overlying telangiectasias

Answer 8

nodular BCC

Question 9

Where is nodular BCC usually found?

Answer 9

head and neck

Question 10

What are features of BCC?

Answer 10

translucent color, telangiectasias, central ulceration, rolled boarder, crusting over

Question 11

pink patch and may even having scaling

Answer 11

superficial BCC

Question 12

What types of BCC would have pigment?

Answer 12

nodular BCC and superficial BCC

Question 13

What are pink or whtite with telangiectasia, plaque and bound down or scar like areas?

Answer 13

Morpheaform/infiltrative/sclerotic BCC

Question 14

What does BCC mimic?

Answer 14

sebaceous hyperplasia

Question 15

How does sebaceous hyperplasia present?

Answer 15

enlarged oil glans, small yellowish papules with central dell, multiple, dermascopy reveals tellangiectasias (not on BCC)

Question 16

What are bnign, small homogenous skin colored to pink papules on nose, no telangiectasias, micmics BCC?

Answer 16

fibrous papule

Question 17

What is the surgical tx for BCC?

Answer 17

curette and desiccation
cryosurgery
excision with 3-4mm margins
mohs

Question 18

What are the nonsurgical tx for BCC?

Answer 18

imiquimod for superficial
5% fluorouracil cream
photodynamic therap
radiation

Question 19

What causes lower recurrance rates?

Answer 19

mohs surgery

Question 20

What are the indications for Mohs?

Answer 20

location - head or hands

aggressive histologic subtype - sclerosing, morpheaform or micronudlar, large tumors, recurrent tumors

Question 21

What are warning signs of BCC?

Answer 21

open sore, reddish patch or irritated area, shiny bump or nodule, pink growth, scar like area