Pseudorabies Flashcards
Causative agent
Porcine herpesvirus 1
All farm animals are susceptible except
Horses
Vaccination?
Regulated/restricted by some states, but can help during an outbreak and to prevent the disease
Virus affects which two organ/body systems
Brain and respiratory
Clinical signs in adults? Mortality rate?
Infection is often unapparent, but stillbirth and abortion are the main CS. Occasionally can see neuro or respiratory signs.
Mortality <15%
Transmission and primary method of spread?
Inhalation
Why is this a concern for public health?
Reportable disease
Most common clinical sign in an adult female pig
Late term abortion
Abortion storms
Stillbirths
Common clinical sign in young pigs? Piglets?
Encephalitis
Piglets - “shaker pig” with high mortality
Zoonotic?
Extremely rare, mild cases.
How long can the virus survive in the environment?
2-7 weeks
Treatment?
No treatment
Common names
Aujesky’s disease
Mad itch
Clinical signs in neonates? Mortality rate?
Fever, convulsions, prostration with rapid death with hours
Mortality rate 100%
Clinical signs in weanlings and growers? Mortality rate?
Pneumonia, pyrexia, tremors
Mortality rate - 15-50%
Prevention?
If diagnosed on a farm, quarantine should be instituted
Don’t be a fomite
Keep other animals away from pigs
Minimize movement of people, animals, objects into pig areas
Add stock from pseudorabies-free herds and test/quarantine
Don’t bring untested animals into a farrowing area
This herpesvirus is resistant against what?
Extreme heat
pH
Diagnosis?
Histology - cowdry type A inclusion bodies (indicates herpes infection). Will find these lesions in resp tract and brain
Serology - ELISA vaccinated animals may test positive.
Clinical signs of pseudorabies in other species
Severe local pruritus that progresses to self mutilation is the main clinical sign. Neuro signs progress to convulsions, paralysis, resp distress, and sudden death.
Natural host and primary reservoir?
Pigs