Hepatobiliary Disease Of The Horse

Question 1

Prognosis for acute serum hepatitis

Answer 1

Guarded to poor

Question 2

What is the most common cause of acute hepatitis and hepatic failure in horses

Answer 2

Acute serum hepatitis

Question 3

Acute serum sickness is associated with administration of what type of medication?

Answer 3

Tetanus antitoxin

Question 4

What are the hallmarks of PA toxicity in the liver

Answer 4

Fibrosis, megalocytosis, bile duct proliferation

Question 5

Is theilers disease acute or chronic hepatitis

Answer 5

Acute

Question 6

CS of acute serum hepatitis/theilers disease

Answer 6

Icterus, photosensitization, hepatoencephalopahty

Others: pica, anorexia, depression, etc

Question 7

What microscopic changes do you see with acute serum hepatitis/theilers

Answer 7

Hepatic necrosis and inflammatory cell infiltrate with mononuclear cells and neutrophils in portal areas along with proliferation of bile ducts

Question 8

Treatment of acute serum hepatitis

Answer 8

Non-specific supportive therapy

Question 9

Chronic active hepatitis causes

Answer 9

Inflammatory response of the liver to an unknown stimulus

Question 10

Chronic active hepatitis CS

Answer 10

Similar to other causes of liver disease, but more chronic

Progressive weight loss, icterus, photosensitization, etc

Question 11

Diagnosis of chronic active hepatitis

Answer 11

Varying degrees of fibrosis in portal areas

Hepatocytes may appear normal

Question 12

Treatment of chronic active hepatitis

Answer 12

Steroids, supportive care, fluids, abx if suspect bacterial cause

Question 13

Cause of PA toxicity

Answer 13

Consumption of plants with PA

Senecia, Croats aria, heliotropium

Question 14

What is megalocytosis

Answer 14

Large liver cells as a result of not being able to divide due to the PA toxin

Question 15

CS of PA toxicity

Answer 15

Non-specific liver signs, icterus, photosensitization

Question 16

Treatment of PA toxicity

Answer 16

Supportive care