BVD Flashcards
What type of virus is BVD
RNA virus - pestivirus in the family flaviviridae
BVD is related to which other two viruses
Classical swine fever
Border disease virus of sheep
Virus classification
Type 1 and type 2 based on genotype
Each genotype can be cytopathic or non-cytopathic
Describe the subclinical form
Animals are not ill, but have antibody present
Describe the acute BVD form
Most common in cattle 6-24 months of age
CS: fever, anorexia, oculonasal discharge, oral ulcers, diarrhea
Virus damages epithelium of mouth, esophagus, intestine, and bronchi
Immunosuppression and pneumonia
Hemorrhagic form
Virus induced thrombocytopenia
What reproductive losses are there?
Infertility
Embryonic death
When does embryonic death/abortion occur
Any stage of gestation
What stage of gestation do you see congenital defects and what defects do you see?
100-150 days
Hydrocephalus, cerebellar hypoplasia, ocular defects, brachygnathia, hypothrichosis
What stage in gestation will you get a PI calf?
40-125 days
Why are PI calves important?
They act as a reservoir (consistently shedding) and is how BVD is maintained in a herd
How do cows get the mucosal form of BVD
They are superinfected with a CP biotype
Why is mucosal form important?
Mucosal disease is a peracute often fatal attack of BVD
Diagnosis of BVD
Based on antigen detection - fluorescent antibody, immunohistochemistry, ELISA
There are other ways to diagnose too - seemed less important
Differentials for BVD
MCF Rinderpest FMD Vesicular stomatitis Bovine papular stomatitis
