Prof Russell Tutorial #2 Flashcards
key features of inflammatory pain?
improves with movement worse with rest morning stiffness swelling erythema
what are the 2 types of joint complications in IBD: UC Crohn’s?
small joint arthritis
Axial arthropathy
axial arthropathy in UC associated with which joints?
sacroileitis
what is a crystal arthropathy?
gout
Describe the location, histology, pattern and treatment for crohn’s?
transmural
granulomas
skips lesions
no J-pouch surgery
Describe the location, histology, pattern and treatment for UC?
starts in rectum
neutrophils
not patchy
surgery - J Pouch surgery
what is colitis mean?
bloody diarrhoea
12 causes of colitis?
Ulcerative Crohn’s Bacterial infection- salmonella, shigella, campylobacter Clostridium difficile subsequent to antibiotic use Entamoeba histolytica infection Neutropenic Radiotherapy Viral infection- CMV Ischaemic- due to arterial disease Collagenous colitis (though this causes more of a watery diarrhea.) Often associated with NSAIDs and coeliac disease Oral contraceptive pill use? Vasculitis
what infections cause colitis?
salmonella
shigella
campylobacter
C. Diff
What virus causes colitis?
CMV
before prescribing steroids what 4 things to ask?
TB
HIV
Strongyloids
Hep B (chronic)
6 organs affected by IBD?
Joints Liver Skin Eye Brain Kidney
what is PSC? what does it lead to?
primary sclerosing cholangitis, leads to biliary cirrhosis
where can NSAIDS cause ulceration?
from oesophagus to small/large bowel, not just stomach
small bowel diarrhoea characteristics?
watery
secretory
voluminous
