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Jason's MD2 Dr. Hogan Tuts > Citroni Tutorial #3 > Flashcards

Citroni Tutorial #3 Flashcards

1
Q

What is SIRS stand for?

A

systemic inflammatory response syndrome

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2
Q

what happens in SIRS?

A

fenetrations in the intravascular compartment get larger, too much Na+ in ECF

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3
Q

where does H20 go in the compartments?

A

EVERYWHERE (all 3)

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4
Q

What is the 3rd space?

A

ECF

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5
Q

what holds water in the ECF?

A

glycoprotein matrix

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6
Q

what holds water in the intracellular compartment?

A

Na/K+ pump

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7
Q

what does Na/K+ pump do to intracellular and ECF?

A

makes a concentration gradient

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8
Q

is ECF usually measured?

A

only in pathology, etc. ascites

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9
Q

what holds fluid in the intravascular compartment?

A

Albumin

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10
Q

conc. of K+ intracellular?

A

~140mmol/L

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11
Q

conc. of K+ intravascularly?

A

3.5-5mmol/L

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12
Q

conditions where you get hypervolaemia?

A

Heart and liver failure

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13
Q

what happens in isovolaemia?

A

increased H20, normal Na+

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14
Q

what conditions cause isovolaemia?

A

H20 intoxication

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15
Q

what can severe hyponatraemia cause?

A

cerebral oedema

seizures

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16
Q

2 causes of hypovolaemia?

A

thiazides

addisonian state

17
Q

why do you not give 5% dextrose after surgery?

A

due to SAADH, would cause H20 toxicity

18
Q

How to correct acute Hyponatraemia?

A

quickly up to symptom relief (no seizures around 115-120), then go slow up to 140

19
Q

side effect of overcorrection of hypoNa+?

A

CPM

central pontine myelosis

20
Q

how slow to correct chronic hypo-natraemia?

A
21
Q

is normal saline normal? why?

A

Nope: 150mmol/L of Cl when physiological is (95-105)

22
Q

Diabetes insipidus urine output can be?

A

> 200-1000ml/hr

23
Q

how does ADH work?

A

aquaporins translocate to collecting ducts, absorbs water

24
Q

specific gravity of someone with D.I.?

A
25
Q

what happens to urine and serum in SIADH?

A

concentrated urine

low serum osmolality

Jason's MD2 Dr. Hogan Tuts (32 decks)

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