Principles of Pharmacology - Part 2

Question 1

Drug use: Detection of diseases

Answer 1

Diagnosis

Question 2

Drug use: alleviation of severity of a disease (mostly incurable)

Answer 2

Mitigation

Question 3

Drug use: stops diseases before they even infect

Answer 3

Prevention

Question 4

Drug use: treatment of diseases

Answer 4

Cure of diseases

Question 5

(T/F) The several thousand drugs that are currently available can be arranged into about 80 groups.

Answer 5

False (70 Groups)

Question 6

(T/F) Many of the drugs within each group have very similar pharmacodynamic actions, and pharmacokinetics properties.

Answer 6

True

Question 7

It is the first drug molecule to be discovered in a group that gives the most important characteristics in the group

Answer 7

Prototype

Question 8

(T/F) The size and molecular weight of a drug will not affect how the drug will be absorbed in the body.

Answer 8

False (size and mw matters)

Question 9

Size and MW: Majority of drugs have a MW of between ______

Answer 9

100 MW - 1000 MW

Question 10

Drugs sizes can range from ________ to over _________

Answer 10

7 MW (Lithium)
50,000 MW (Thrombolytic enzymes, proteins)

Question 11

Generally, to achieve selective binding, a drug must have a MW of __________

Answer 11

100 MW

Question 12

(T/F) Drugs that are over 1000 MW are readily absorbed.

Answer 12

False (Poorly Absorbed)

Question 13

Drug-Receptor Bonds: Strongest bond created by the sharing of electrons that yields irreversible action

Answer 13

Covalent Bonds

Question 14

Drug-Receptor Bonds: Bonds between a cation and an anion

Answer 14

Electrostatic Bonds

Question 15

Drug-Receptor Bonds: It is the weakest type of bond

Answer 15

Van der Waals

Question 16

(T/F) The drug shape must be complementary to the receptor.

Answer 16

True

Question 17

Term used for compounds that have the same chemical formula but different structure or spatial arrangement.

Answer 17

Chirality