Exam 1

Question 1

A quaternary ammonium compound that
cannot penetrate membranes, rapidly hydrolyzed and has large IV bolus injection

Answer 1

Acetylcholine

Question 2

Is more resistant to enzymatic hydrolysis than
ACh. Not used clinically

Answer 2

METACHOLINE (Mecholyl)

Question 3

very potent choline ester having both
muscarinic and nicotinic effects. used for glaucoma

Answer 3

CARBACHOL

Question 4

Not hydrolyzed by cholinesterases, Treatment of gastric retention, postoperative abdominal
distention, nonobstructive urinary
retention, paralytic ileus

Answer 4

BETANECHOL (Urecholine)

Question 5

from leaves of Pilocarpus jaborandi, has muscarinic action similar to Ach. used for glaucoma (miosis)

Answer 5

PILOCARPINE

Question 6

plant derivative similar to nicotine

Answer 6

Lobeline

Question 7

from mushroom Amanita muscaria, causes mushroom poisoning

Answer 7

Muscarine

Question 8

From Areca nut (Areca catechu)

Answer 8

ARECOLINE