PRELIM 03 - Granules

Question 1

Are agglomerates of powdered materials; provides a pleasant vehicle for selected drugs with bitter and salty taste

Answer 1

Granules

Question 2

2 methods of granule preparation

Answer 2

Wet granulation, Dry granulation

Question 3

2 methods of wet granulation

Answer 3

Basic wet method, Fluid bed processing

Question 4

Involves moistening the powder, passing the paste through a screen, placing it in drying trays, and drying it under heat to create granules (Methods of wet granulation)

Answer 4

Basic wet method

Question 5

Forms granules or pellets; particles in conical piece of equipment are dispersed and suspended (Methods of wet granulation)

Answer 5

Fluid bed processing

Question 6

Nmt 60% thru a No. 40 sieve (USP standard for drugs and chemical powders)

Answer 6

Coarse (No. 20 sieve), Moderately coarse (No. 40 sieve)

Question 7

No limit to greater fineness (USP standard for drugs and chemical powders)

Answer 7

Fine (No. 80 sieve), Very fine (No. 120 sieve)

Question 8

Other name for dry granulation

Answer 8

Dry method, Fusion method

Question 9

Method where a dry powder is passed through a roller compactor and then through a granulating machine (Methods of granule preparation)

Answer 9

Dry granulation

Question 10

Also known as a roll press or roller compactor; processes a find powder into dense sheets or forms

Answer 10

Roll compactor

Question 11

Process that involves compression of a powder or powder mixture under 8000-1200 pounds of pressure

Answer 11

Slugging

Question 12

Products of slugging; are flat faced and about 2.5 cm (1 in) in diameter

Answer 12

Slugs

Question 13

Refers to the science of small particles

Answer 13

Micromeritics