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[2ND YEAR] PH 107.1 - Pharmaceutical Dosage Forms, Drug Delivery Systems, and Medical Devices (Lab) > FINAL 05 - Emulsions (Mineral Oil Emulsion) > Flashcards

FINAL 05 - Emulsions (Mineral Oil Emulsion) Flashcards

1
Q

A 2 phase system in which one liquid is dispersed in the form of small globules throughout another liquid in which it is immiscible

A

Emulsion

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2
Q

3 components of emulsions (IEE)

A

Internal phase, External phase, Emulsifying agent

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3
Q

Emulsion diluted with water/aqueous preparation

A

O/W emulsion

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4
Q

Emulsion diluted with oleaginous/oil miscible liquid

A

W/O emulsion

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5
Q

Phase that contains water-soluble drugs, preservatives, coloring, and flavoring agents

A

Aqueous phase

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6
Q

Phase that contains fixed/volatile drugs (oil, oil-soluble vitamins, and antiseptic)

A

Oil phase

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7
Q

Added to prevent auto-oxidation of the oil and rancidity or destruction of any vitamin resent

A

Antioxidant

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8
Q

Includes carbohydrates and gelatins; produce O/W emulsions (Types of emulsifying agents)

A

Natural emulsifying agents

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9
Q

Examples include stearyl alcohol, cetyl alcohol, and glyceryl monostearate; produce O/W emulsions (Types of emulsifying agents)

A

High molecular weight alcohols

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10
Q

__________ is employed in externally used emulsion; produce W/O emulsions

A

Cholesterol

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11
Q

Includes colloidal clays such as bentonite, magnesium hydroxide, and aluminum hydroxide; produce O/W emulsions (Types of emulsifying agents)

A

Finely divided solids

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12
Q

May be anionic, cationic, or nonionic (Types of emulsifying agents)

A

Synthetic (Wetting agents)

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13
Q

Includes triethanolamine oleate and sodium lauryl sulfate (Types of synthetic emulsifying agents)

A

Anionic

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14
Q

Includes benzalkonium chloride (Types of synthetic emulsifying agents)

A

Cationic

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15
Q

Includes lecithin (Types of synthetic emulsifying agents)

A

Amphoteric

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16
Q

Includes sorbitan esters, polyethylene glycol 400 monostearate, and polyoxyethylene sorbitan esters (Types of synthetic emulsifying agents)

A

Nonionic

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17
Q

May be O/W or W/O (Types of emulsions)

A

Simple

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18
Q

May be O/W/O or W/O/W (Types of emulsions)

A

Multiple

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19
Q

Most stable emulsion; the dispersed phase is in very small globules (Types of emulsions)

A

Microemulsion

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20
Q

Emulsifying agent and water is added first, then oil (Methods of emulsion preparation)

A

English/Wet method

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21
Q

Emulsifying agent and oil is added first, then water (Methods of emulsion preparation)

A

Continental/Dry method

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22
Q

Shaking vigorously (Methods of emulsion preparation)

A

Forbes/Bottle method

23
Q

Hand homogenizer (Methods of emulsion preparation)

A

Auxiliary method

24
Q

Calcium soap and soft soap (Methods of emulsion preparation)

A

Nascent/In situ soap method

25
Q

100 A (10 microns) (Methods of emulsion preparation)

A

Microemulsion

26
Q

Temporary separation of the 2 phases (Problems encountered in emulsions)

27
Q

Total separation of the 2 phase with coalescence (Problems encountered in emulsions)

28
Q

Evaporation of water; O/W becomes W/O (Problems encountered in emulsions)

A

Phase inversion

29
Q

Add drop of water, O/W (Methods of identifying emulsions)

A

Drop dilution test

30
Q

Oil soluble - Sudan red, W/O; Water soluble - Amaranth green, O/W (Methods of identifying emulsions)

A

Dye solubility test

31
Q

Water conduct electricity, O/W (Methods of identifying emulsions)

A

Electronic conductivity test

32
Q

Oil can absorb UV light, W/O (Methods of identifying emulsions)

A

Fluorescence test

33
Q

Mineral oil emulsion (Category)

A

Oral emulsion

34
Q

Mineral oil emulsion (Synonym)

A

Liquid petrolatum emulsion

35
Q

Mineral oil emulsion (Use)

A

Lubricating cathartic

36
Q

Mineral oil emulsion is employed as a lubricating cathartic with a usual dose of __________

37
Q

__________ is used as a cathartic in Mineral oil emulsion

A

Mineral oil

38
Q

__________ is used as a suspending or emulsifying agent Mineral oil emulsion

39
Q

__________ is used as a sweetening agent in Mineral oil emulsion

40
Q

__________ is used as a flavorant in Mineral oil emulsion

41
Q

__________ is used as a preservative in Mineral oil emulsion

42
Q

Emulsion came from the word __________ which means to ‘milk out’

43
Q

Refers to the dispersed phase

A

Internal phase

44
Q

Refers to the dispersion medium

A

External phase

45
Q

Emulsion that has an oleaginous internal phase and aqueous external phase

A

O/W emulsion

46
Q

Emulsion that has an aqueous internal phase and oleaginous external phase

A

W/O emulsion

47
Q

3rd component present in an emulsion

A

Emulsifying agent

48
Q

Exposed surface of liquids tend to contract (Theories on emulsification)

A

Surface tension theory

49
Q

They facilitate the breaking up of larger molecules into smaller ones, having less tendency to coalesce

A

Surfactants

50
Q

Certain emulsifying agents orient themselves about and within a liquid (Theories on emulsification)

A

Oriented-wedge theory

51
Q

Emulsifying agent surrounds the droplets of the internal phase as a thin layer of film (Theories on emulsification)

A

Plastic/Interfacial film theory

52
Q

Viscosity of an emulsion aids emulsification (Theories on emulsification)

A

Viscosity theory

53
Q

Mineral oil emulsion (2 labels) (WS)

A

Official white label, Shake well label

54
Q

Mineral oil emulsion (Container)

A

30 mL wide-mouthed amber bottle

[2ND YEAR] PH 107.1 - Pharmaceutical Dosage Forms, Drug Delivery Systems, and Medical Devices (Lab) (37 decks)

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