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PH 107.1 - Pharmaceutical Dosage Forms, Drug Delivery Systems, and Medical Devices (Lab) > MIDTERM 01 - Ointments > Flashcards

MIDTERM 01 - Ointments Flashcards

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USMLE® Step 1 flashcards
1
Q

A semisolid preparation intended for external application to skin and mucous membrane

A

Ointment/Salve/Charisma

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2
Q

2 types of ointments

A

Medicated, Non-medicated

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3
Q

Used for treatment of cutaneous diseases, and has local and systemic effects (Types of ointments)

A

Medicated ointment

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4
Q

Referred to as “ointment bases”; used for their physical effects such as a protectant, emollient or lubricating effects, or use as vehicles in medicated ointments (Types of ointments)

A

Non-medicated ointment

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5
Q

2 methods of ointment preparation (MF)

A

Mechanical incorporation/Levigation, Fusion

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6
Q

Reducing to impalpable powder to reduce grittiness and form a very smooth nucleus (Methods of ointment preparation)

A

Mechanical incorporation/Levigation

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7
Q

Involves heating first the substance with high melting point like wax and spermaceti using water bath before adding soft, oleaginous material (Methods of ointment preparation)

A

Fusion

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8
Q

__________ are bases used for medicated ointments

A

Ointment bases

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9
Q

Has an emollient effect; it remains on the skin for long periods and is difficult to wash off (Types of ointment bases)

A

Oleaginous bases/Hydrocarbon bases

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10
Q

Purified mixture of semisolid hydrocarbons obtained from petroleum (Levigating agents for oleaginous bases)

A

Petrolatum, USP

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11
Q

Commercial product derived from Petrolatum, USP

A

Vaseline

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12
Q

Wholly or nearly decolorized purified mixture of semisolid hydrocarbons from petrolatum; used for diaper rash and dry skin (Levigating agents for oleaginous bases)

A

White petrolatum, USP

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13
Q

Commercial product derived from white petrolatum, USP

A

White Vaseline

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14
Q

Purified wax obtained from the honeycomb of the bee Apis mellifera; has slightly greater viscosity than plain petrolatum (Examples of oleaginous bases)

A

Yellow ointment, USP

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15
Q

Ointment that consists of white wax and white petrolatum

A

White ointment

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16
Q

Is not easily removed from skin with water washing; possesses some power of penetration into the deepest layers of the skin (Types of ointment bases)

A

Absorption base

17
Q

Has the ability to absorb water with the formation of W/O emulsion; composed of stearyl alcohol, white wax, cholesterol, and white petrolatum

A

Hydrophilic petrolatum

18
Q

Commercial product derived from hydrophilic petrolatum

A

Aquaphor

19
Q

May contain NMT 0.25% water; is insoluble in water but mixes without separation with about 2x its weight in water (Levigating agents for absorption bases)

A

Anhydrous lanolin, USP

20
Q

Synonym for anhydrous lanolin, USP

A

Refined wool fat

21
Q

Obtained from the wool of sheep (Ovis aries); is a purified waxlike substance that is cleaned, deodorized, and decolorized (Levigating agents for absorption bases)

A

Lanolin, USP

22
Q

Synonym for lanolin, USP

A

Hydrous wool fat

23
Q

Is a semisolid white W/O emulsion; used as an emollient and base (Examples of absorption bases)

A

Cold cream, USP

24
Q

It is a W/O emulsion of petrolatum, mineral oil, mineral wax, wool wax, alcohol, and bronopol; is an example of cold cream

A

Eucerin cream

25
Q

Are O/W emulsions resembling creams; the aqueous external phase is easily washed from the skin and can absorb serous discharges

A

Water-removable bases (Water-washable bases)

26
Q

Is employed as a water removable vehicle for medicinal substances (Example of water-removable bases)

A

Hydrophilic ointment

27
Q

Do not contain oleaginous components; are water washable, and often referred to as greaseless (Types of ointment bases)

A

Water-soluble bases

28
Q

An ointment that is a polymer of ethylene oxide and water

A

Polyethylene glycol ointment

29
Q

Formulation (Special ingredient) in white ointment

A

White wax

PH 107.1 - Pharmaceutical Dosage Forms, Drug Delivery Systems, and Medical Devices (Lab) (27 decks)

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