Pregnancy Flashcards
state 3 stages in the ovarian cycle
- follicular growth
- ovulation
- luteal function
what is high at each of the following stages:
- follicular growth
- ovulation
- luteal function
- follicular growth - OESTRADIOL
- ovulation - LH
- luteal function - PROGESTERONE
follicle secretes _____________ but if fertilised, it implants and becomes the corpus lute which secretes _____________
follicle secretes OESTRADIOL but if fertilised, it implants and becomes the corpus lute which secretes PROGESTERONE
the corpus luteum eventually becomes the _________ which secretes _ hormones in which _________ develops breast tissue for breast milk lactation
the corpus luteum eventually becomes the PLACENTA which secretes 3 hormones in which PROLACTIN develops breast tissue for breast milk lactation
name the 3 possible types of diabetes in pregnancy
T1DM
T2DM
GDM (3rd trimester when placenta significantly grows)
what week does foetal organogenesis occur?
week 5
another word for large baby?
macrosomia
3 possible complications of a neonate?
respiratory distress - immature lungs
hypoglycaemia - fits
hypocalcaemia - fits
management of T1DM and T2DM in pregnant women?
folic acid 5mg (very low)
regular eye checks
what drug should you avoid for HBP in pregnancy?
ACEI and statins
use labetalol instead
T1DM drug?
T2DM drug?
GDM drug?
T1DM drug - insulin
T2DM drug - metformin and probably insulin later
GDM drug - lifestyle, metformin and may need insulin
if someone with hypothyroidism becomes pregnant, you must ________ the dose of thyroxine by 25mg
if someone with hypothyroidism becomes pregnant, you must INCREASE the dose of thyroxine by 25mg
hCG increases __________ which suppresses ___
hCG increases THYROXINE which suppresses TSH
hCG causes increased T4 and lowers TSH but causes _____________ ___________ (sickness of pregnancy)
hCG causes increased T4 and lowers TSH but causes HYPEREMESIS GRAVIDARUM (sickness of pregnancy)
Infertility
Spontaneous miscarriage
Stillbirth
Thyroid crisis in labour
Transient Neonatal thyrotoxicosis
can all occur in what?
hyperthyroidism
hyperthyroid management in pregnancy?
wait and see
beta-blockers if needed
low dose ATDs:
propylthiouracil 1st trimester
carbimazole in 2/3rd trimester
what drug can cause the following:
embryopathy in 1st trimeter
scalp abnormalities
GI abnormalities
choanal & oesophageal atresia
carbimazole
what drug can cause the following:
liver toxicity
propylthiouracil
TRAb antibodies can cross the placenta and cause what?
neonatal transient hyperthyroidism
pregnant female at 10 weeks gestation:
high T4
high T3
low TSH
diagnosis?
hyperemesis
