Predicted questions Flashcards

1
Q

What are enzymes

A

Large proteins that catalyse reactions

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2
Q

Explain lock and key theory (4 points)

A
  1. Enzyme has complementary active site to the substrate
  2. The substrate will bind to the active site
  3. Where it will be broken dish until smaller molecules easier to digest
  4. Product is released and enzyme’s active site will remain the same and break down more substrates
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3
Q

What happens to rate of reaction of enzymes as temp increases

A

Rate of reaction increases
Enzyme and substrate molecule move quicker and collide more frequently

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4
Q

What happens at optimum temp for an enzyme

A

The reaction works as fast as possible and is most effective here

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5
Q

What happens to enzyme when temp is too high and past optimum

A

Denature and stop working

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6
Q

What happens when an enzyme denatures

A

Shape of active site will change so substrate can no longer fit into active site so enzyme can not catalyse reaction

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7
Q

Give three digestive enzymes

A

Amylase
Protease
Lipase

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8
Q

Where are the sites of production for amylase enzyme (3)

A

Salivary glands
Pancreas
Small intestine

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9
Q

Where are the 3 sites of production for protease enzymes

A

Stomach
Pancreas
Small intestine

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10
Q

Where are the 2 sites of production for lipase

A

Pancreas and small intestine

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11
Q

What reaction is catalysed with amylase

A

Starch to glucose

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12
Q

What reaction is catalysed by protease

A

Proteins to amino acids

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13
Q

What reaction is catalysed by lipase

A

Lipids to fatty acid and glycerol

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14
Q

What are the two things that can denature and enzyme

A

Extreme of PH or very high temp

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15
Q

Describe the pathway of air

A

Mouth and nose
Trachea
Bronchi
Bronchioles
Alveoli

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16
Q

How are the alveoli adapted for gaseous exchange

A

Good blood supply
Large SA
Capillaries and alveoli are one cell thick so diffusion distance is shorter
Moist walls

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17
Q

Explain steps of gaseous exchange

A
  1. We inhale and alveoli fill with oxygen
  2. Blood in capillaries surrounded is deoxygenated so containing lots of carbon dioxide
  3. Oxygen diffuses down the concentration gradient into capillary bloodstream which has low concentration of oxygen
  4. Carbon dioxide diffuse downs it’s concentration gradient into alveoli
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18
Q

What does TMV stand for and what organism does it affect

A

Tobacco mosaic virus
Plants

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19
Q

How is TMV spread

A

Direct contact with infected plants
Animal and plant vectors
Soil: pathogen remains in soil

20
Q

What are the TMV symptoms

A

Mosaic pattern of discolouration (yellow) on leaves where chlorophyll is destroyed
Stunted growth due to reduced ability to photosynthesise

21
Q

How is TMV prevented

A

Pest control
Growing TMV resistant strains

22
Q

What can alcohol lead to

A

Liver disease
Impaired brain function
Affected development of unborn babies

23
Q

What are the effects of the risk factors for alcohol

A

Liver cirrhosis - liver cannot remove toxins and produce enough bile for digestion
Damages brain and causes anxiety and depression
Alcohol can pass through placenta risking miscarriage, premature birth, birth defects

24
Q

What is cancer the result of

A

Changes in cells that lead to uncontrolled growth and division by mitosis

25
What forms a tumour
Rapid division of abnormal cells
26
What are malignant tumours
Cancerous tumours that can spread to other tissues and parts of the body by breaking off into bloodstream forming secondary tumours
27
What are benign tumours
Non cancerous that do not spread
28
What are some examples of carcinogens
Tar in cigarettes Ultra violet rays from sun or tanning beds Genetic factors Alcohol
29
What is the equation for aerobic respiration words and formula
Glucose + oxygen —> carbon dioxide + water C6H12O6 + 6O2 —> 6CO2 + 6H2O
30
What is the equation for anaerobic respiration in muscles word and formula
Glucose —> lactic acid + energy C6H12O6 —> 2C3H6O3
31
What is aerobic respiration
Respiration with oxygen
32
What is anaerobic respiration
Respiration in the absence of oxygen
33
What is the energy released during respiration used for
Chemical reactions to build larger molecules Muscle contraction for movement Keeping warm
34
Definition of metabolism
The sum of all the reactions in a cell or the body
35
What is done with energy released by respiration in cells - metabolism
Continual enzyme controlled processes of metabolism that produce new molecules
36
Give 2 metabolic processes related to carbohydrates
Synthesis of carbohydrates from sugars (starch, glycogen, cellulose) Breakdown of glucose in respiration to release energy
37
Give 3 metabolic reactions associated with proteins
Synthesis of amino acids from glucose and nitrate ions Amino acids to form proteins Excess proteins broken down to form urea for excretion
38
Give the metabolic reaction associated to lipids
Synthesis of lipids from one molecule of glycerol and three molecules of fatty acid
39
Why is anaerobic respiration only for a short amount of time (3)
Muscles become fatigued and stop contracting Do not have enough energy to be released to continue Lactic acid builds up
40
What are the stages of clinical trails with explanations
Preclinical trails: drug tested in cells, tissues, live animals Clinical trails: healthy volunteers receive low dose to see if safe and effective Larger numbers of volunteers then receive drug to find optimum dose Peer review: results will be tested and checked by independent researchers Double blind trails and placebo
41
Why are new drugs tested and trailed
To find Toxicity Efficacy Dose
42
How does the skin protect us from pathogens (4)
Physical barrier Produces antimicrobial secretions Microorganisms loving on skin prevent pathogens growing Platelets in blood form scabs at wounds
43
How does the nose/breathing system prevent entry of pathogens
Cilia and mucus trap particles in air preventing them from reaching the lungs Trachea and bronchi produce mucus that traps pathogens which is moved away from lungs
44
How does the stomach prevent entry of pathogens
Hydrochloride acid and the low pH destroys pathogens in food and mucus
45
How do the eyes prevent entry of pathogens
Produce tears that contain enzymes to kill bacteria and are antiseptic