Pre-release

Question 1

What are oncogenes

Answer 1

Genes that code for the transition of one stage in the cell cycle to the next
-ve epigenetic changes can lead to excessive cell division

Question 2

What are tumour suppressor genes?

Answer 2

Are genes that produce suppressor proteins to stop the cell cycle
-ve if mutated can cause cell cycle to be continous

Question 3

How did WW discover right dosage?

Answer 3

Gradually increased dosage. Until patients reacted badly. Then decreased it slightly

Question 4

What is the point of Phase I in a clinical trial?

Answer 4

Test for side effects. Use a small number of healthy people

Question 5

What is the point of Phase II in a clinical trial?

Answer 5

Use patients and double blind trials. Compare effectiveness

Question 6

What is the point of Phase III in a clinical trial?

Answer 6

Larger sample size. Double blind. Compare to existing treatment

Question 7

Describe how a safe dosage of cancer drug could be determined

Answer 7

Test on healthy people
Then test on cancer patients
Increase dosage until there are significant side effects

Question 8

Why is ATP required for glycolysis?

Answer 8

Provide energy
For reaction to occur
Provide phosphate for phosphorylation to make GALP