Pre/post operative care Flashcards
When should you stop ferrous sulphate prior to colonoscopy
7 days as can effect purgative effectiveness
Bowel regime for bowel imaging
ERCP- Clotting, antibiotics, Vitamin K if jaundiced
Diagnostic OGD- Nil by mouth for 6 hours
Flexible sigmoidoscopy- Phosphate enema 30 minutes pre procedure
Colonoscopy- Check U+E and if normal, prescribe oral purgatives e.g. picolax
Fluid management of surgical patients
Hartmann’s when a crystalloid is needed for resuscitation or replacement of fluids.
Avoid 0.9% N. Saline (due to risk of hyperchloraemic acidosis) unless patient vomiting or has gastric drainage.
Use 4%/0.18% dextrose saline or 5% dextrose in maintenance fluids.
Causes of pyrexia post op
Actelectasis - abdo surgery, mild pyrexia, chest signs- within 48hrs
UTI- indwelling catheter,
Wound infection- erythema, mild pyrexia- 5-7 days
Anastomotic leak- swinging fevers, ileus -7d
Surgical patients requiring thromboprophylaxis
Surgery greater than 90 minutes at any site or greater than 60 minutes if the procedure involves the lower limbs or pelvis
Acute admissions with inflammatory process involving the abdominal cavity
Expected significant reduction in mobility
Age over 60 years
Known malignancy
Thrombophilia
Previous thrombosis
BMI >30
Taking hormone replacement therapy or the contraceptive pill
Varicose veins with phlebitis
What reduces the effectiveness of local
Infected tissue
Acidotic environment- ionise in alkaline
Doses of local
Agent Dose plain Dose with adrenaline
Lignocaine 3mg/Kg 7mg/Kg
Bupivacaine 2mg/Kg 2mg/Kg
Prilocaine 6mg/Kg 9mg/Kg
Optimal fluid management pre op for elective
Avoid solids 6 hours
Clear fluids until 2 hours
Carb loading drink in between
Avoid IV fluids
Monitoring of heparin
APTT
No need for LMWH
Different types of central lines and there uses
Central tunnelled- Hickman, good for long term therapeutic
Non tunneled
PICC- less complications on insertion
More prone to infection
Thromboprophyaxis in paediatric cases
None
Chemical types of local
All amino amide
Apart from procaine and benzocaine- Amino ester
Absolute CI to tourniquet
AV fistula
Severe peripheral vascular disease
Previous vascular surgery
Bone fracture or thrombosis at the site of tourniquet application
Physiological effects of inflating then deflating the tourniquet
Post inflation
Increased systemic vascular resistance, increased CVP and increased BP
Slower gradual increase in BP over time
Induced hypercoagulable state
Slow increase in core temperature
Post deflation
Fall in CVP, BP and SVR
Increased end tidal carbon dioxide
Enhanced fibrinolysis
Fall in core temperature
Raised serum potassium and lactate levels
Factors effecting wound healing
Mnemonic to remember factors affecting wound healing: DID NOT HEAL
D iabetes
I nfection, irradiation
D rugs eg steroids, chemotherapy
N utritional deficiencies (vitamin A, C & zinc, manganese), Neoplasia
O bject (foreign material)
T issue necrosis
H ypoxia
E xcess tension on wound
A nother wound
L ow temperature, Liver jaundice
CI of lidocaine
Any cardiac rhythm disorders
Urine sodium in dehydration
<20mmol
Biochem features of dehydration
Hypernatraemia
Rising haematocrit
Metabolic acidosis
Rising lactate
Increased serum urea to creatinine ratio
Urinary sodium <20 mmol/litre
Urine osmolality approaching 1200mosmol/kg
Closure for peri anal abscess
Secondary closure
Dyes or injections prior to surgeries
Parathyroid surgery; consider methylene blue to identify gland.
Sentinel node biopsy; radioactive marker/ patent blue dye.
Surgery involving the thoracic duct; consider administration of cream.
Metallic heart valves anticoagulants prior to surgery
Bridge to heparin
Stop this 6 hrs prior to surgery
Local used in regional block
Prilocaine
Due to less cardiotoxic
Use of lidocaine vs bupivacaine
It has a much longer duration of action than lignocaine and this is of use in that it may be used for topical wound infiltration at the conclusion of surgical procedures with long duration analgesic effect.
Lidocaine faster onset
Presentation of atelectasis post op
w/i first 48hrs
Mild pyrexia
Dyspnoea
Dull bases ̄c ↓AE
Mx of wound dehiscence
Replace abdo contents and cover ̄c sterile soaked gauze
IV Abx: broad spec
Opioid analgesia
Call senior and arrange theatre
Repair in theatre
Wash bowel
Debride wound edges
Close ̄c deep non-absorbable sutures (e.g. nylon)
May require VAC dressing or grafting
RF for wound dehiscence
Pre-Operative Factors
↑ age
Smoking
Obesity, malnutrition, cachexia
Comorbs: e.g. BM, uraemia, chronic cough, Ca Drugs: steroids, chemo, radio
Operative Factors
Length and orientation of incision
Closure technique: follow Jenkin’s Rule Suture material
Post-operative Factors
↑ IAP: e.g. prolonged ileus → distension Infection
Haematoma / seroma formation
Mx of post op ileus
IV fluids and NGT
TPN if prolonged
Cause of reduced urine output post op
Post-renal
Commonest cause
Blocked / malsited catheter Acute urinary retention
Pre-renal: hypovolaemia
Renal: NSAIDs, gentamicin
Anuria usually = blocked or malsited catheter
Oliguria usually = inadequate fluid replacemen
When is heparin given in vascular and cardiac bypass surgeries
Vascular- 3,000 units of systemic heparin 3-5 minutes prior to cross clamping
Bypass- 30,000 units is given prior to going on cardiopulmonary bypass
A thin bluish - white margin appears around the graft
Re epithelierisation
LA for scalp lesions
Lidocaine with adrenaline
Wound healing process
Haemostasis
Inflammation- Typically days 1-5
Neutrophils migrate into wound (function impaired in diabetes).
Growth factors released, including basic fibroblast growth factor and vascular endothelial growth factor.
Fibroblasts replicate within the adjacent matrix and migrate into wound.
Macrophages and fibroblasts couple matrix regeneration and clot substitution.
Regeneration
Typically days 7 to 56
Platelet derived growth factor and transformation growth factors stimulate fibroblasts and epithelial cells.
Fibroblasts produce a collagen network.
Angiogenesis occurs and wound resembles granulation tissue.
Remodelling
From 6 weeks to 1 year
Longest phase of the healing process and may last up to one year (or longer).
During this phase fibroblasts become differentiated (myofibroblasts) and these facilitate wound contraction.
Collagen fibres are remodeled.
Microvessels regress leaving a pale scar.
How should DM be managed intra operatively
Cases operated on first
Sliding scale for insulin or poorly controlled- K supplementation
Options for surgical nutrition and when they are used
Nutrition requirements < 4 wks:
Fine bore NG tube as well as oral diet
(bike accident, head injury, comatose, no basal skull #; slow recovery;)
Naso-jejanal for acute severe pancreatitis
Nutrition requirements > 4 wks :
PEG (most case)
NCJ (Needle Catheter Jejunostomy);
Use after major GI surgery; Small bowel stoma done
TPN use
Pre-operative pt. & needs to be optimized prior 2surgery
Low BMI & Low albumin
Projectile vomiting due 2PS occurred due to obstructing tumor(excludes oral /NG route) Post operative entero-cutaneous fistula
Patients identified as being malnourished
BMI < 18.5 kg/m2
* unintentional weight loss of > 10% over 3-6/12
* BMI < 20 kg/m2 and unintentional weight loss of > 5% over 3-6/12
Parenteral nutrition guidelines
for feeding < 14 days consider feeding via a peripheral venous catheter
* for feeding > 30 days use a tunneled subclavian line
* continuous administration in severely unwell patients
* if feed needed > 2 weeks consider changing from continuous to cyclical feeding
* don’t give > 50% of daily regime to unwell patients in first 24-48h
Those at risk of referring syndrome
BMI < 16 kg/m2
- Unintentional weight loss >15% over 3-6 months
- Little nutritional intake > 10 days
- Hypokalaemia, Hypophosphataemia or hypomagnesaemia prior to feeding (unless high)
Kcal aim for refeeding syndrome risk and those are who aren’t
10/kcal/kg per day- RS
25- not as risk
When is cell salvage CI
Malignancy
Physiological response to surgery
Neuro- sympathetic
Acute phase response- TNF-α, IL-1, IL-2, IL-6, interferon and prostaglandins are released
Endocrine
Increases ACTH and cortisol production:
increases protein breakdown
increases blood glucose levels
* Aldosterone increases sodium reabsorption
* Vasopressin increases water reabsorption and causes vasoconstriction
Causative agents of malignant hyperthermia
Halothane
Suxamethosium
Cause, ix and mx of malignant hyperthermia
Excessive release of Ca
Hyperpyrexia and rigidity
CK raised
Dantrolene
Spinal anaesthesia SE
hypotension, sensory and motor block, nausea and urinary retention.
Epidural use and disadvantages
preferred option following major open abdominal procedures
- Disadvantages of epidurals is that they usually confine patients to bed, especially if a motor block is present. In addition an indwelling urinary catheter is required. Which may not only impair mobility but also serve as a conduit for infection. They are contraindicated in coagulopathies.
When TAP blocks are used, which LA
extensive laparoscopic abdominal procedures
Bupivicaine
What do you prepare skin with
skin with alcoholic chlorhexidine (Lowest incidence of SSI)
When do prophylactic antibiotics needs to be given
placement of prosthesis or valve
- clean-contaminated surgery - (e.g resp GI)
contaminated surgery - If a tourniquet is to be used, give prophylactic antibiotics earlier
Types of wound contamination
Clean : Non-infected skin with no hollow organ is cut
Clean-contaminated : Cut of hollow organ except COLON (e.g. GB, unruptured Appendix)
Contaminated : Colon incision; open #; animal/ human bites; colon insion ē minimal spillage.
Dirty : Perforation; wounds made in presence of pus; perforated viscus/traumatic wound>4hrs
Mx options for wound dehiscence
Resuture- wound edges healthy- deep tension sutures used
Wound dressing- granulation tissue, high output bowel fistula
Bogota bag-if wound cannot be closed- need theatre return
+ diagnostic peritoneal lavage
-RBC>100000/mm .
- WBC> 500/mm3
- Gm staining showing organisms
Indications of preoperative steroid cover
Pituitary or adrenal surgery
>10mg 3m
Evidence of cushing
Mx of pts on pre op steroids
For patient on >10mg pred for 3m
Usual dose +
Minor surgery- 50mg pre op HC IV
25mg every 8hrs for 24hrs
Intermediate- 50mg pre op and 25mg every 8h for 24 hrs
Major- 100mg pre, 200mg infusion >24hrs
Warfriin before surgery
Stop 3-5d before
Heparin bridge
INR <1.2 open surgery, 1.5 invasive procedures
Antiplatelets before surgery
Stop 7d-14 before
When to stop LMWH before surgery
6hrs
Metformin before surgery
Stop 48 hours before
In what timeframe should you delay surgery if there’s been a CVA
<6w
Aim to wait for 6m
What is a ring block
Field block in digit or penis
Levels where brachial plexus block is performed
Intersclaene- trunks
supra/infraclavicualr - divisions
axillary - cords
Femoral block
1cm lateral to pulsation of femoral artery at inguinal ligament
Sciatic block
Lateral, anterior or posterior
2cm lateral to ischial tuberosity
Intercostal nerve block
Feel posterior angle of rib
Insert needle just below edge of rib
Complications of epidural
Post dural tap headache
Infection
Haematoma
Urinary retention
When should spinal catheters be removed when anti coagulated
12 hours post LMWH
Then can restart AC after 2 hours
ASA classification
1- normal
2- mild disease
3-severe that limits activity but not incapacitating
4- constant threat to life
5- not expected to survive
DIfferent inductive agents
Thiopental sodium - negative inotrope, cheaper, not used with laryngeal
Propofol - antiemetic effect, used if using laryngeal mask
Etomidate- better for CV unstable pats- induces adrenal suppression
Muscle relaxants
Suxamtheonium- depolarising- hydrolysed slower than Ach
Non depolarising- slower onset, longer duratioon
Acracurium, vecuronium
GA maintainence drugs
Halothane
Enflurane
Isolfurance
NO
Antidote for prilocaine
Methylene blue
May be used in piere block
Which surgeries would be scarless
Fetal
Formation of scar
Haemastasis- mins to hours- vasospasm, fibrin clot- platelets
Next stages can happen concurrently
Inflammation Days, neutrophil, macrophage, fibroblast
Regen 7d-2m- weeks - fibroblast- produce collagen, endothelial cells, macrophages
Remodelling 1m-1y- myofibroblasts, vessels regress
Hypertrophic vs keloid scar
Hypertrophic- stay within scar limit- can be excised
Keloid- do not respect limit- cannot be excised - steroids, silicone
Which factors is affected by warfarin
2,7,9,10 protein C
What increases vs inhibits warfarin
Increase- by inhibiting CYP450
Cipro/cimetidine
Omeprazole/ Fluconazole/metronidazole
Valproate
Erythromycin
Inhibit
Rifampicin
Barbituates
Carbmazepine
CI for caudal anaesthesia
Spina bifida
Meningitis
RICP
Spinal anaesthesia location, dose, how quickly the effect
L1/2
In subarachnoid
2.5-3.5 buvi
2-5 mins
Block more dense
Headache more common
Hypotension more rapid
Epidural anaesthesia location, dose, onset
Between dura mate and ligaments flavum
15-20 of buvi
15-20 mins
Hypotension low
Headache not as common
Patient has bone mets not controlled on medication what to do
Radiotherapy
Patient has pancreatic mets not controlled on medication what to do
Coeliac block
Patient with oesophectomy that’s unsafe to swallow mx
Jejunostomy as stomach now intrathoracic
Nasaljujenal benefits and placement
Less food pooling
Less aspiration risk
Placed surgically
Long term TPN effect on liver
Fatty liver
Derranged LFT
A calculi cholecystitis
Feeding for perforated oesophagus
TPN
Pancreatitis with poor appetite feeding
Nasal jejenostomy
Head injury no signs of skull base fracture feeding
NG tube
Subtotal colectomy with poor appetite feeding
NG tube
High output fistula feeding
TPN
Crohns disease with multiple fistula
TPN
When is TAP block administered
During operation
When is a tracheostomy performed
If requiring ventilation over roughly 1m- long term
Useful for slow wheaning
To reduce dead space
When is a laryngeal mask used and what risks
Short day surgery
Swift onset anaesthesia - fluranes, no muscles relaxants needed
Used in paediatric
Poor control of reflux
Fever and diarrhoea in leukaemia post transfusion
GVHD- immunocomprismed
What day after transfusion does GVHD occur
4-30d GVHD
Cells found in TRALI
Neutrophils