Postlab quiz 6 Flashcards
What is stargardt’s disease also known as
fundus flavimaculatus
Stargardt’s disease is the most common from of this
juvenile macular degeneration
Stargardt’s disease is the loss of this
central vision between the ages of 6 and 20
Stargardt’s disease starts as this
presence of small, yellow spots in eye
With stargardt’s disease vision loss begins this way then quickly does this
slowly
escalates
Causes of stargardt’s disease
Very strong genetic component
Mutation of the gene ABCA4 (one of 21 genes coding for the retina)
Stargardt’s disease: 90% of the cases are this
autosomal recessive
Stargardt’s disease: Specific cause
a dysfunctional protein is made which does not allow normal transport of energy from the photoreceptors centered in the macula lutea
Stargardt’s disease: Lipofuscin build up can result in this
an imbalance between formation and disposal mechanisms in the eye, and is related to the muation in the ABCA4 gene
Stargardt’s disease: The gene is also associated with this
vitamin A processing
Stargardt’s disease: signs and symptoms
blurry/distorted vision loss of fine focusing difficulty recognizing familar faces can lead to blindness deterioration of light sensitive cells color vision affected in late stages
Stargardt’s disease: children with the disease will have difficulty doing this
reading
Stargardt’s disease: treatment
no cure
little can slow progression
wearing sunglasses may slow progression
avoiding excessive vitamin A and Beta-carotene
Stargardt’s disease: excessive vitamin A and Beta-carotene do this
promote accumulation of lipofuscin
Stargardt’s disease: prognosis
No cure
eventually leads to blidness in most cases
Stargardt’s disease: affects this many Americans, and has a frequency of this in children
25000 Americans
1 in 10000 children
Primary sex organs: male, females
testes
ovaries
Sperm and ovum are these types of cells and are denoted in this manor
gamates, haploid
n
Fertilization results in this
zygot
Sex chromosomes: male, female
XY
XX
The zygot grows through
mitosis
These develop in early male embryo
seminiferous tubules
intersitial cells
Indifferent gonads are found at this stage
early embryonic
This determines if indifferent gonads will form testes or ovaries, and results from this
TDF, testes determining factory.
SRY gene on Y chromosome
When do the ovaries develop in the embryo
follicles do not develop until third trimester
Testes produce these two things
testosterone
Mullerian inhibition factor (MIF)
MIF degenerates this
Paramesonephric (mullerian) duct
The paramesonephric (mullerian) duct becomes this in men, and this in woman
Degenerates in men
froms uterus and uterine tubes in females
Epididymides, ductus deferentia, ejaculatory ducts are formed from this in the presence of this
mesonephric (wolffian) duct
testosterone
This happens to the mesonephric (wolffian) duct in females
degenerates because there is no testosterone
other embryonic structures in the presence of testosterone become these
prostate
penis
scrotum
other embryonic structures without the presence of testosterone become these
vagina
labia
clitoris
At this time an ultrasound can be used to determine the sex of an embryo/child
12-13 week
Two structures that regulate gonadal function
hypothalamus
anterior pituitary
THis is released by the hypothalamust and affects this organ
gonadaltropic releasing hormone (GnRH)
anterior pituitary
THis is released by the anterior pituitary in response to GnRH
Gonadotropins (FSH and LH)
FSH stands for
folical stimulating hormone
LH stands for
Leutinizing hormone
T/F: FSH and LH are found in only females
F, found in both males and females
Gonadotropins act on this
gonads
What are the sex steroids
testosterone
estrogen
In the presence of gonadotropins the gonads release/produce this
sex steroids
inhibin
gamets
Sex steroids have this type of affect on the hypothalamus and anterior pituitary
negative
primary sex organ in the male
testis
testes produce this
sperm
Sperm moves from the testes to exit the penis through these structures (in order)
epididymis ductus (vas) deferens ampulla ejaculatory duct urethra
maturation of the sperm takes place in this structure
epididymis
the ampulla, seminal vesicle and prostate form this
ejaculatory duct
Important glands in the male reproductive tract
seminal vesicle
prostate
bulbourethral gland
The external urethral orifice is associated with this part of the penis
glans penis
Hormonally the imporant part of the male reproductive tract is his
testes
Testes contain this important structures
seminferous tubules
intersitital (leydig) cells
sperm is produced in this structure
seminiferous tubles
injected testosterone does this
negatively effects the hypothalamus and anterior pituitary causing FSH and LH to stop being released
shrinks testes
Process of producing sperm is known as
spermatogenesis
Steps of sperm production in the testes
some spermatogonia undergo mitosis
other spermatogonia undergo meiosis and form primary spermatocytes
Primary spermatocyes undergo meiosis and from secondary spermatocytes
secondary spermatocytes undergo meiosis and form spermatids
Spermatids mature into spermatezoa
The maturation from spermatids to spermatezoa is know as
spermiogenesis
Primary female sex organ
ovary
Important female reproductive structures
vagina
uterus
overy
uterine tubes
Eggs are release from the overies into this structure
uterine tube towards the uterus
Fertilization takes place here
uterine tube
The zygote develops here
uterus
How long is the egg viable after ovulation
24 hours
Sperm can live this long
36-48 hours within the female reproductive tract
Layers of the uterus
perimetrium
myometrium
endometrium
perimetrium tissue type and function
connective tissue
site of attachement to peritoneal cavity
myometrium tissue type and function
smooth muscle
contractions during labor to assist in delivery of fetus